Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues.

Scoliosis

The presence of an abnormal lateral curvature of the spine.


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PMID (PMCID)
17587623
MALE
Langerhans cell histiocytosis as a possible differential diagnosis of painful scoliosis.
Huang KY, Lin RM, Yan JJ, Lin CJ.
Joint Bone Spine. 2007;74(4):396-9.
We report on a 5-year 8-month-old boy suffering from spinal Langerhans cell histiocytosis (LCH), who had initial symptoms of back and abdominal pain, as well as tilting of the shoulder that mimicked hemivertebra of T10 with scoliosis, as revealed by radiography.
3350958
MALE
Histiocytosis X with scoliosis and osteolysis.
Wroble RR, Weinstein SL.
J Pediatr Orthop. 1988;8(2):213-8.
Severe progressive scoliosis and massive osteolysis of both femoral shafts occurred in conjunction with the Hand-Schuller-Christian form of histiocytosis X.