Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues.

Melanoma

The presence of a melanoma, a malignant cancer originating from pigment producing melanocytes. Melanoma can originate from the skin or the pigmented layers of the eye (the uvea).


合計: 10

                       


（表示件数）
PMID (PMCID)
30216522
 MALE
Granulomatous dermatitis secondary to vemurafenib in a child with Langerhans cell histiocytosis.
Chen L, Hsi AC, Kothari A, Dehner LP, Hayashi RJ, Coughlin CC.
Pediatr Dermatol. 2018;35(6):e402-e403.
Vemurafenib currently has Food and Drug Administration approval for the treatment of BRAF V600E+ metastatic melanoma in adults, but recent discoveries of BRAF V600E in more than half of tested Langerhans cell histiocytosis lesions have prompted clinical trials of vemurafenib therapy for children with refractory, multisystem Langerhans cell histiocytosis.
30216522
 MALE
Granulomatous dermatitis secondary to vemurafenib in a child with Langerhans cell histiocytosis.
Chen L, Hsi AC, Kothari A, Dehner LP, Hayashi RJ, Coughlin CC.
Pediatr Dermatol. 2018;35(6):e402-e403.
Vemurafenib currently has Food and Drug Administration approval for the treatment of BRAF V600E+ metastatic melanoma in adults, but recent discoveries of BRAF V600E in more than half of tested Langerhans cell histiocytosis lesions have prompted clinical trials of vemurafenib therapy for children with refractory, multisystem Langerhans cell histiocytosis.
30402364
(6200441)
 OTHER
Sporotrichoid Keratoacanthomas: Case Report and Review of Neoplasms Presenting in a Sporotrichoid Pattern.
Abudu B, Cohen PR.
Cureus. 2018;10(8):e3196.
These included squamous cell carcinoma (three patients), lymphoma (two patients), and one patient with each of the following: epithelioid sarcoma, Langerhans cell histiocytosis, melanoma, and peripheral nerve sheath tumor.
30402364
(6200441)
 OTHER
Sporotrichoid Keratoacanthomas: Case Report and Review of Neoplasms Presenting in a Sporotrichoid Pattern.
Abudu B, Cohen PR.
Cureus. 2018;10(8):e3196.
Keratoacanthomas can be added to the list of cancers (which include squamous cell carcinoma, lymphoma, epithelioid sarcoma, Langerhans cell histiocytosis, melanoma, and peripheral nerve sheath tumor) whose skin lesions have appeared in a sporotrichoid distribution.
19739348
 MALE Middle Aged
[Primary bone anaplastic large cell lymphoma].
Mandujano-Alvarez GJ, Moreno-Sanchez F, Morales-Polanco M, Garcia-Ortiz JR, Ortiz-Hidalgo C.
Acta Ortop Mex. 2009;23(3):142-8.
The differential diagnoses include osteomyelitis, small round cell tumors, mainly Ewing sarcoma/PNET, metastatic carcinoma, melanoma, Hodgkin lymphoma and Langerhans' cell histiocytosis.
18806499
 MALE Middle Aged
Langerhans cell histiocytosis mimicking malignant melanoma: a diagnostic pitfall.
Billings TL, Barr R, Dyson S.
Am J Dermatopathol. 2008;30(5):497-9.
Langerhans cell histiocytosis mimicking malignant melanoma: a diagnostic pitfall.
19094486
 MIXED_SAMPLE Young Adult
[Interdigitating dendritic cell sarcoma/tumor: a study of 3 cases].
Gan MF, Lu HS, Zhang JW, Yu XR.
Zhonghua Bing Li Xue Za Zhi. 2008;37(10):676-9.
It needs to be distinguished from follicular dendritic cell sarcoma, inflammatory pseudotumor, Langerhans' cell histiocytosis, malignant melanoma, undifferentiated carcinoma and anaplastic large cell lymphoma.
14987233
 MIXED_SAMPLE Infant
Interdigitating dendritic cell sarcoma: a report of four paediatric cases and review of the literature.
Pillay K, Solomon R, Daubenton JD, Sinclair-Smith CC.
Histopathology. 2004;44(3):283-91.
The differential diagnosis includes inflammatory pseudotumour, follicular dendritic cell sarcoma, true histiocytic lymphoma, malignant Langerhans cell histiocytosis, anaplastic large-cell lymphoma, melanoma, and a range of sarcomas.
12362286
 MALE Middle Aged
Pulmonary Langerhans' cell histiocytosis (histiocytosis X) following metastasizing malignant melanoma.
Tirilomis T, Zenker D, Mirzaie M, Dalichau H.
Swiss Med Wkly. 2002;132(21-22):285-7.
Chemotherapy for malignant melanoma may be related to the development of pulmonary Langerhans' cell histiocytosis.
12362286
 MALE Middle Aged
Pulmonary Langerhans' cell histiocytosis (histiocytosis X) following metastasizing malignant melanoma.
Tirilomis T, Zenker D, Mirzaie M, Dalichau H.
Swiss Med Wkly. 2002;132(21-22):285-7.
To our knowledge this is the first reported case of pulmonary Langerhans' cell histiocytosis in association with malignant melanoma.