Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues.

Sarcoma

A connective tissue neoplasm formed by proliferation of mesodermal cells. Bone and soft tissue sarcomas are the main types of sarcoma. Sarcoma is usually highly malignant.


Total: 13

                       


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PMID (PMCID)
30885248
 FEMALE Child
Langerhans cell histiocytosis presenting as eosinophilic granuloma of the bilateral forearms in an 8-year-old girl: a case report.
Idrissa S, Cherrabi H, Efared B, Sidibe K, Attaraf K, Chater L, Afifi A.
J Med Case Rep. 2019;13(1):67.
Langerhans cell histiocytosis should be included in the differential diagnosis of osteomyelitis and Ewing's sarcoma.
28630846
(5458704)
 OTHER
Chronic Recurrent Multifocal Osteomyelitis: A Case Report with Atypical Presentation.
Figueiredo MP, Pato M, Amaral F.
J Orthop Case Rep. 2017;7(1):75-78.
The differential initially included Ewing's sarcoma, osteosarcoma, subacute osteomyelitis, and Langerhans cell histiocytosis.
27194875
(4860914)
 OTHER
A rare spindle-cell variant of non-Hodgkin's lymphoma of the mandible.
Srikant N, Yinti SR, Baliga M, Kini H.
J Oral Maxillofac Pathol. 2016;20(1):129-32.
A working diagnosis of a spindle-cell sarcoma was arrived at with various differentials provided such as fibrosarcoma, rhabdomyosarcoma, leiomyosarcoma, malignant peripheral nerve sheath tumor, Langerhans cell histiocytosis and lymphoma and stating the need for immunohistochemistry to subtype the tumor.
27152444
 FEMALE Young Adult
Immunohistochemical evaluation of p16 expression in cutaneous histiocytic, fibrohistiocytic and undifferentiated lesions.
Smith EH, Lowe L, Harms PW, Fullen DR, Chan MP.
J Cutan Pathol. 2016;43(8):671-8.
We evaluated p16 expression in a cohort of histiocytic (reticulohistiocytoma, Langerhans cell histiocytosis, xanthogranuloma, Rosai Dorfman disease and xanthoma), fibrohistiocytic (dermatofibroma, epithelioid fibrous histiocytoma and dermatofibrosarcoma protuberans) and undifferentiated (atypical fibroxanthoma and pleomorphic undifferentiated sarcoma) lesions.
25007664
 MIXED_SAMPLE Child
[Diagnosis and management of nasal and pharyngeal dendritic cell tumor-case report and literature review].
Dan LV, Huang Y, Yang H, Liu S, Wang H, Wang M.
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2014;28(8):522-6.
Four cases of nasal and pharyngeal dendritic cell tumor were described, including two cases of follicular dendritic cell sarcoma (FDCS), one case of Langerhans cell histiocytosis (LCH) and one case of Langer hans cell sarcoma (LCS).
16024682
 MALE
Histiocytic sarcoma in a 3-year-old male: a case report.
Buonocore S, Valente AL, Nightingale D, Bogart J, Souid AK.
Pediatrics. 2005;116(2):e322-5.
His tumor progressed during chemotherapy designed for Langerhans' cell histiocytosis and sarcoma.
14987233
 MIXED_SAMPLE Infant
Interdigitating dendritic cell sarcoma: a report of four paediatric cases and review of the literature.
Pillay K, Solomon R, Daubenton JD, Sinclair-Smith CC.
Histopathology. 2004;44(3):283-91.
The differential diagnosis includes inflammatory pseudotumour, follicular dendritic cell sarcoma, true histiocytic lymphoma, malignant Langerhans cell histiocytosis, anaplastic large-cell lymphoma, melanoma, and a range of sarcomas.
9126048
 MALE Middle Aged
Soft tissue Langerhans' cell histiocytosis in an adult. A case presentation with flow cytometric analysis and literature review.
al-Abbadi M, Masih A, Braylan RC, Almasri NM.
Arch Pathol Lab Med. 1997;121(2):169-72.
To our knowledge, this is the first reported case of solitary Langerhans' cell histiocytosis in an adult in which the presentation mimicked sarcoma.
8636815
 OTHER Child
Pleuropulmonary blastoma: a marker for familial disease.
Priest JR, Watterson J, Strong L, Huff V, Woods WG, Byrd RL, Friend SH, Newsham I, Amylon MD, Pappo A, Mahoney DH, Langston C, Heyn R, Kohut G, Freyer DR, Bostrom B, Richardson MS, Barredo J, Dehner LP.
J Pediatr. 1996;128(2):220-4.
The diseases found to be associated with PPB include other cases of PPB, pulmonary cysts, cystic nephromas, sarcomas, medulloblastomas, thyroid dysplasias and neoplasias, malignant germ cell tumors, Hodgkin disease, leukemia, and Langerhans cell histiocytosis.
7993260
 MALE Child
Unifocal Langerhans' cell histiocytosis (eosinophilic granuloma) resembling Ewing's sarcoma.
Biswal BM, Lal P, Uppal R, Mallik S.
Australas Radiol. 1994;38(4):313-4.
Unifocal Langerhans' cell histiocytosis (eosinophilic granuloma) resembling Ewing's sarcoma.
3510049
 MALE Middle Aged
Composite lymphoma with immunoblastic features and Langerhans' cell granulomatosis (histiocytosis X).
Almanaseer IY, Kosova L, Pellettiere EV.
Am J Clin Pathol. 1986;85(1):111-4.
The lymph node biopsy showed a composite lymphoma (follicular, mixed, small and large cell plus B-immunoblastic sarcoma) with associated focal Langerhans' cell granulomatosis (LCG) (Histiocytosis X).
3510049
 MALE Middle Aged
Composite lymphoma with immunoblastic features and Langerhans' cell granulomatosis (histiocytosis X).
Almanaseer IY, Kosova L, Pellettiere EV.
Am J Clin Pathol. 1986;85(1):111-4.
The lymph node biopsy showed a composite lymphoma (follicular, mixed, small and large cell plus B-immunoblastic sarcoma) with associated focal Langerhans' cell granulomatosis (LCG) (Histiocytosis X).
280425
 MALE
Childhood leukemia presenting as a diaphyseal radiolucency.
Bos GD, Simon MA, Spiegel PG, Moohr JW.
Clin Orthop Relat Res. 1978;(135):66-8.
An open biopsy was performed because of an initial clinical diagnosis of osteomyelitis, histiocytosis X or a round cell sarcoma.