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Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues.

Germinoma

A type of undifferentiated germ cell tumor that may be benign or malignant.

Total: 7

(per page)

PMID (PMCID)
26527477	MALE
	Solitary Langerhans cell histiocytosis located in the neurohypophysis with a positive titer HCG-beta in the cerebrospinal fluid.
	Kinoshita Y, Yamasaki F, Usui S, Amatya VJ, Tominaga A, Sugiyama K, Kurisu K. Childs Nerv Syst. 2016;32(5):901-4.
	Under a preoperative diagnosis of germinoma, a biopsy was performed from the posterior pituitary lobe via the transsphenoidal endoscopic approach and the histological diagnosis was revealed to be Langerhans cell histiocytosis (LCH).
26331225	FEMALE	Middle Aged
	Autoimmune central diabetes insipidus in a patient with ureaplasma urealyticum infection and review on new triggers of immune response.
	Murdaca G, Russo R, Spano F, Ferone D, Albertelli M, Schenone A, Contatore M, Guastalla A, De Bellis A, Garibotto G, Puppo F. Arch Endocrinol Metab. 2015;59(6):554-8.
	The most common and well recognized causes include local inflammatory or autoimmune diseases, vascular disorders, Langerhans cell histiocytosis (LCH), sarcoidosis, tumors such as germinoma/craniopharyngioma or metastases, traumatic brain injuries, intracranial surgery, and midline cerebral and cranial malformations.
23108562	MIXED_SAMPLE	Child
	Endoscopic biopsies of lesions associated with a thickened pituitary stalk.
	Jinguji S, Nishiyama K, Yoshimura J, Yoneoka Y, Harada A, Sano M, Fujii Y. Acta Neurochir (Wien). 2013;155(1):119-24; discussion 124.
	Histopathological examinations of all the lesions confirmed diagnoses of germinoma in four patients, hypophysitis in three, Langerhans cell histiocytosis in two, craniopharyngioma in one, and cancer metastasis in one.
17978791	FEMALE
	[Polyuria and polydipsia in a 5 year-old child: diagnostic problems].
	Di Dio G, Zanetta F, Zanetta S, Petri A, Bellone S, Bona G. Minerva Pediatr. 2007;59(6):813-6.
	In particular, CDI can be caused by lesions like germinoma and craniopharyngioma, Langerhans'cell histiocytosis, inflammatory, autoimmune and vascular diseases, trauma resulting from surgery or an accident; and in rare cases, genetic defects in the synthesis of vasopressin that are inherited as autosomal dominant or X-linked recessive traits.
15942956	FEMALE	Child
	Central diabetes insipidus: Is it Langerhans cell histiocytosis of the pituitary stalk? A diagnostic pitfall.
	Prosch H, Grois N, Bokkerink J, Prayer D, Leuschner I, Minkov M, Gadner H. Pediatr Blood Cancer. 2006;46(3):363-6.
	In pediatric and adolescent patients the most common causes for CDI are Langerhans cell histiocytosis (LCH) and germinoma.
11098641	FEMALE	Child
	Langerhans cell histiocytosis limited to the pituitary-hypothalamic axis--two case reports.
	Isoo A, Ueki K, Ishida T, Yoshikawa T, Fujimaki T, Suzuki I, Sasaki T, Kirino T. Neurol Med Chir (Tokyo). 2000;40(10):532-5.
	Langerhans cell histiocytosis rarely presents as a solitary lesion in the pituitary-hypothalamic region, and is indistinguishable from germinoma, which occurs much more frequently, especially in Japanese.
9833893	MIXED_SAMPLE	Child
	Virtual MRI endoscopy of the intracranial cerebrospinal fluid spaces.
	Shigematsu Y, Korogi Y, Hirai T, Okuda T, Ikushima I, Sugahara T, Liang L, Ge Y, Takahashi M. Neuroradiology. 1998;40(10):644-50.
	We investigated the potential of the intracranial virtual MRI endoscopy applied to visualisation of the pathology in 13 patients with surgically confirmed trigeminal neuralgia (3), hemifacial spasm (3), acoustic neuroma (3), suprasellar germinoma (1), Langerhans cell histiocytosis (1), lateral ventricle nodules (1) and pituitary dwarfism (1).