Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues.

Thyroiditis

Inflammation of the thyroid gland.


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PMID (PMCID)
27867869
 OTHER
Thyroid Langerhans cell histiocytosis and papillary thyroid carcinoma.
AlZahrani R, Algarni M, Alhakami H, AlSubayea H, Alfattani N, Guler M, Satti M.
Gland Surg. 2016;5(5):537-540.
Comprehensive patient evaluation including FNAC with papillary thyroid cancer result then she underwent total thyroidectomy and bilateral neck dissection and final histologic examination confirmed papillary thyroid carcinoma in the background of lymphocytic thyroiditis, associated with Langerhans cell histiocytosis (LCH).
20038929
 MALE Middle Aged
Lymphocytic hypophysitis with dacryoadenitis in a male patient: non-invasive diagnosis and high-dose methylprednisolone pulse therapy.
Lu Z, Li J, Ba J, Yang G, Dou J, Mu Y, Lu J.
Neuro Endocrinol Lett. 2009;30(6):700-4.
It is often detected in patients with other autoimmune systemic diseases such as Hashimoto's thyroiditis, epinephritis, megaloblastic anemia, and Langerhans cell histiocytosis.
12446922
 FEMALE Adult
Incidental langerhans cell histiocytosis of thyroid: case report and review of the literature.
Foulet-Roge A, Josselin N, Guyetant S, Gardet JJ, Besancon A, Saint-Andre JP, Fabiani B.
Endocr Pathol. 2002;13(3):227-33.
We report a case of a 42-yr-old woman with Langerhans cell histiocytosis (LCH) confined to the thyroid and associated with lymphocytic thyroiditis and a papillary microcarcinoma.
9510462
 FEMALE Child
Primary hypothyroidism, central diabetes insipidus and growth hormone deficiency in multisystem Langerhans cell histiocytosis: a case report.
Rami B, Schneider U, Wandl-Vergesslich K, Frisch H, Schober E.
Acta Paediatr. 1998;87(1):112-4.
Langerhans cell histiocytosis should be included in the differential diagnosis in cases with pituitary stalk thickening and additional hypothalamic/pituitary hormone deficiencies, and in cases of acquired primary hypothyroidism, with or without enlargement of the thyroid gland and ultrasound findings similar to thyroiditis.
8932433
 MALE Adult
Langerhans cell histiocytosis isolated to the thyroid gland.
Thompson LD.
Eur Arch Otorhinolaryngol. 1996;253(1-2):62-5.
A case of Langerhans cell histiocytosis isolated to the thyroid gland associated with lymphocytic thyroiditis is presented and clinical implications are discussed.