Serotonin syndrome

Serotoninergic syndrome is characterised by an excess of serotonin in the central nervous system, associated with the use of various agents, including selective serotonin reuptake inhibitors (SSRIs).

Hyperactivity

Hyperactivity is a state of constantly being unusually or abnormally active, including in situations in which it is not appropriate.


Total: 6

                       


(per page)
PMID (PMCID)
30318504
(6196581)
 FEMALE Middle Aged
Case of Serotonin Syndrome Initially Presenting as Diffuse Body Pain.
Guo MH, Monir RL, Wright A, Holland NP.
Am J Case Rep. 2018;19:1227-1231.
Primary features of serotonin syndrome include mental status changes, autonomic hyperactivity, and neuromuscular abnormalities.
22452676
 MALE Adult
Probable drug-drug interaction leading to serotonin syndrome in a patient treated with concomitant buspirone and linezolid in the setting of therapeutic hypothermia.
Morrison EK, Rowe AS.
J Clin Pharm Ther. 2012;37(5):610-3.
The symptoms associated with serotonin syndrome can include hyperthermia, mental status changes, autonomic hyperactivity and neuromuscular abnormalities, all of which can be concealed in the critically ill patient owing to concomitant therapies.
21491099
 MIXED_SAMPLE
Serotonin toxicity: a short review of the literature and two case reports involving citalopram.
Talarico G, Tosto G, Pietracupa S, Piacentini E, Canevelli M, Lenzi GL, Bruno G.
Neurol Sci. 2011;32(3):507-9.
The serotonin toxicity is often described as a clinical triad of mental-status changes (agitation and excitement with confusion), autonomic hyperactivity (diaphoresis, fever, tachycardia, and tachypnea), neuromuscular abnormalities (tremor, clonus, myoclonus, and hyperreflexia) and, in the advanced stage, spasticity; not all of these findings are consistently present.
19697589
 FEMALE Adult
The serotonin syndrome: initial misdiagnosis.
Attar-Herzberg D, Apel A, Gang N, Dvir D, Mayan H.
Isr Med Assoc J. 2009;11(6):367-70.
Serotonin toxicity should be considered in patients in whom the combination of mental changes, neuromuscular abnormalities and autonomic hyperactivity are features of acute disease.
19544673
 MALE Adult
A case of serotonin syndrome associated with methadone overdose.
Martinez TT, Martinez DN.
Proc West Pharmacol Soc. 2008;51:42-4.
These symptoms are characteristic of serotonin syndrome which is often described as mental status changes, autonomic hyperactivity, and neuromuscular abnormalities.
17187532
 FEMALE
A case of serotonin syndrome and mutism associated with methadone.
Bush E, Miller C, Friedman I.
J Palliat Med. 2006;9(6):1257-9.
Serotonin syndrome is often described as a clinical triad of mental status changes, autonomic hyperactivity, and neuromuscular abnormalities, but not all of these findings are consistently present in all patients with the disorder.