Leishmaniasis

A parasitic disease caused by different species of the genus <i>Leishmania</i>, transmitted through the bite of hematophagous female phlebotomine sand flies. The clinical spectrum ranges from asymptomatic to clinically overt disease which can remain localized to the skin or disseminate to the upper oral and respiratory mucous membranes or throughout the reticulo-endothelial system. Three main clinical syndromes have been described: visceral (or Kala-Azar; with fever, weight loss, hepatosplenomegaly), cutaneous, and mucocutaneous leishmaniasis (cutaneous or mucocutaneous ulceration).

Weight loss

Reduction inexisting body weight.


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PMID (PMCID)
30787856
 OTHER
Visceral Leishmaniasis and Glomerulonephritis: A Case Report.
Alwazzeh MJ, Alhashimalsayed ZH.
Saudi J Med Med Sci. 2019;7(1):40-43.
Clinical presentations of visceral leishmaniasis include recurrent fever, substantial weight loss, hepatosplenomegaly and anemia.
23682278
(3655258)
 OTHER
Bone marrow negative visceral leishmaniasis in an adolescent male.
Jetley S, Rana S, Khan S, Zeeba J, Hassan M, Kapoor P.
Iran J Parasitol. 2013;8(1):182-5.
In endemic areas, the constellation of fever, progressive weight loss, weakness, pronounced splenomegaly, anemia, leukopenia, and hypergammaglobulinemia is highly suggestive of visceral leishmaniasis.
23121063
 MALE Adult
[Febrile pancytopenia and hepatosplenomegaly as leading symptoms of visceral leishmaniasis].
Polak P, Svoboda R, Kubakova P, Brychtova Y, Panovska A, Nohynkova E, Husa P, Freibergerova M, Paizkova R, Snelerova M, Pychova M, Kamelander J.
Vnitr Lek. 2012;58(10):761-4.
The authors present a case report of a patient with febrile pancytopenia, hepatosplenomegaly and weight loss as main symptoms of visceral leishmaniasis.
21776599
 MIXED_SAMPLE Infant
[Evaluation of visceral leishmaniasis diagnosis using indirect fluorescent antibody tests in 4 pediatric patients].
Balc YI, Turk M, Ozgur A, Kucuktasc K.
Turkiye Parazitol Derg. 2011;35(2):114-6.
Visceral Leishmaniasis (VL) in infancy is mostly seen between the ages of 2-4,and visceral infection causes long standing fever, weakness, weight loss, hepatosplenomegaly and pancytopenia.
17896607
 MIXED_SAMPLE Infant
Profile of fatal visceral leishmaniasis at an Indian tertiary care center.
Malatesha G, Mathur P, Madan K, Samanta P, Samantaray JC.
Trop Gastroenterol. 2007;28(1):28-31.
Visceral leishmaniasis is a highly morbid and incapacitating infection, which usually presents with prolonged fever, weight loss and hepato-splenomegaly.
17315475
 MALE Adult
[Diffuse cutaneous leishmaniasis in a patient with AIDS].
Perez C, Solias Y, Rodriguez G.
Biomedica. 2006;26(4):485-97.
A patient with a leishmaniasis-Aids co-infection was presented and discussed.. A 29-year -old soldier, coming from the Province of San Jose del Guaviare, Colombia, complained of a weight loss of 18 kgs in the previous ten months as well as a two-month-old cutaneous leision.
16927925
 FEMALE Adult
[Visceral leishmaniasis--surgical aspects].
Onita M, Hornung E, Ciobanu C, Sarbu AE, Olariu T, Onita C, Stoica AL.
Chirurgia (Bucur). 2006;101(3):335-9.
Visceral Leishmaniasis is a multi-organic parasitic disease caused by an intracellular protozoon named Leishmania Donovani; the mean signs are: weight loss, cough, fever, hepatosplenomegaly, adenopathy and cutaneous lesions; death without treatment is the rule.