Leishmaniasis

A parasitic disease caused by different species of the genus <i>Leishmania</i>, transmitted through the bite of hematophagous female phlebotomine sand flies. The clinical spectrum ranges from asymptomatic to clinically overt disease which can remain localized to the skin or disseminate to the upper oral and respiratory mucous membranes or throughout the reticulo-endothelial system. Three main clinical syndromes have been described: visceral (or Kala-Azar; with fever, weight loss, hepatosplenomegaly), cutaneous, and mucocutaneous leishmaniasis (cutaneous or mucocutaneous ulceration).

Anemia

A reduction in erythrocytes volume or hemoglobin concentration.

Total: 14

(per page)

PMID (PMCID)
30787856	OTHER
	Visceral Leishmaniasis and Glomerulonephritis: A Case Report.
	Alwazzeh MJ, Alhashimalsayed ZH. Saudi J Med Med Sci. 2019;7(1):40-43.
	Clinical presentations of visceral leishmaniasis include recurrent fever, substantial weight loss, hepatosplenomegaly and anemia.
30083074	OTHER
	Kala-Azar and leukemia: A rare association.
	Bay A, Aktekin EH, Eksi F, Ozcan M. Turk Pediatri Ars. 2018;53(1):45-47.
	Anemia, leucopenia, and thrombocytopenia are the main hematologic abnormalities commonly seen in visceral leishmaniasis.
23682278 (3655258)	OTHER
	Bone marrow negative visceral leishmaniasis in an adolescent male.
	Jetley S, Rana S, Khan S, Zeeba J, Hassan M, Kapoor P. Iran J Parasitol. 2013;8(1):182-5.
	In endemic areas, the constellation of fever, progressive weight loss, weakness, pronounced splenomegaly, anemia, leukopenia, and hypergammaglobulinemia is highly suggestive of visceral leishmaniasis.
26157823 (4435270)	OTHER
	Visceral Leishmania as Unusual Cause of Splenic Peliosis in the United States.
	Ghazzawi Y, Absah I. ACG Case Rep J. 2013;1(1):61-3.
	Visceral leishmaniasis should be considered in cases of marked splenomegaly, anemia, and thrombocytopenia, especially with a history of visiting an endemic area.
22370845	MALE	Child
	Splenectomy in a patient with treatment-resistant visceral leishmaniasis: a case report.
	Dutra RA, Dutra LF, Reis Mde O, Lambert RC. Rev Soc Bras Med Trop. 2012;45(1):130-1.
	Visceral leishmaniasis (VL), also known as Kala-azar, is a systemic infection caused by a protozoan (Leishmania) and, in its classic form, is a serious illness associated with malnutrition, anemia, hepatosplenomegaly, infectious processes and coagulopathies.
22393633	MALE	Child
	[Visceral leishmaniasis: pediatric case report observed outside the traditional foci in Cameroon].
	Mbassi Awa HD, Pondy A, Njiki Kinkela M, Lebela J, Koki Ndombo PO. Med Trop (Mars). 2011;71(6):618-20.
	The purpose of this report is to describe an autochtonous case of visceral leishmaniasis with cachexia, fever, splenomegaly, ascitis and severe anemia observed in an eight-year-old boy from a region in eastern Cameroon outside the traditional disease foci.
20064986	MALE	Adult
	Autochthonous visceral leishmaniasis in a human immunodeficiency virus (HIV)-infected patient: the first in thailand and review of the literature.
	Suankratay C, Suwanpimolkul G, Wilde H, Siriyasatien P. Am J Trop Med Hyg. 2010;82(1):4-8.
	We report a case of visceral leishmaniasis in a human immunodeficiency virus (HIV)-infected 37-year-old Thai fisherman who presented with nephritonephrotic syndrome, fever, anemia, and thrombocytopenia.
17483492	FEMALE
	Immune mediated hemolysis in visceral leishmaniasis.
	Mahajan V, Marwaha RK. J Trop Pediatr. 2007;53(4):284-6.
	Anemia in visceral leishmaniasis is a usual manifestation; however, Coombs positive hemolytic anemia has been infrequently reported.
12219147	MALE	Adult
	Concurrent cutaneous, visceral and ocular leishmaniasis caused by Leishmania (Viannia) braziliensis in a kidney transplant patient.
	Gontijo CM, Pacheco RS, Orefice F, Lasmar E, Silva ES, Melo MN. Mem Inst Oswaldo Cruz. 2002;97(5):751-3.
	The first clinical signs of leishmaniasis included fever, thoracic pain, hepatosplenomegaly, leucopenia and anemia.
12458816	FEMALE	Infant
	Visceral leishmaniasis and Coombs' positive hemolytic anemia: a rare association in an infant treated with liposomal amphotericin B.
	Dilber E, Erduran E, Isik Y. Turk J Pediatr. 2002;44(4):354-6.
	Visceral leishmaniasis is a worldwide, disseminated intracellular protozoal infection that usually manifests by fever, hepatosplenomegaly, anemia, thrombocytopenia, leukopenia and hypergammaglobulinemia.
7885958	MALE	Infant
	[Anemia and hepatosplenomegaly: search for the protozoon?].
	La Placa G, Muschiato M, Arlati S, Urbano M, Verdura C. Pediatr Med Chir. 1994;16(5):475-7.
	An eight-months-old infant presenting with anemia, hepatosplenomegaly, hypoalbuminemia and polyclonal hypergammaglobulinemia was finally found to be affected by visceral leishmaniasis, after having suspected oncohaematologic problems.
2193355	MALE	Adult
	Bacterial infection as a presenting manifestation of visceral leishmaniasis.
	Garces JM, Tomas S, Rubies-Prat J, Gimeno JL, Drobnic L. Rev Infect Dis. 1990;12(3):518-9.
	We conclude that in areas where leishmaniasis is endemic, early bone marrow aspirate should, in most instances, be performed in patients with bacterial infection associated with anemia, leukopenia, or thrombocytopenia if hepatomegaly and/or splenomegaly is present.
2833465	MIXED_SAMPLE	Adult
	Immunological studies of pancytopenia in visceral leishmaniasis.
	Pollack S, Nagler A, Liberman D, Oren I, Alroy G, Katz R, Schechter Y. Isr J Med Sci. 1988;24(2):70-4.
	We report three cases of combined anemia, neutropenia and thrombocytopenia in patients with visceral leishmaniasis (kala-azar).
6533607	MALE
	[Visceral leishmaniasis. Practical considerations on a clinical case].
	Ronconi GF, Gualandi V, Bertoli GL, Ronconi M, Valli F. Pediatr Med Chir. 1984;6(4):575-7.
	A male infant with profound anemia and liver and spleen enlargement was affected by visceral Leishmaniasis.