Leprechaunism

Leprechaunism is a congenital form of extreme insulin resistance (a group of syndromes that also includes Rabson-Mensenhall syndrome, type A insulin-resistance syndrome, and acquired type B insulin-resistance syndrome; see these terms) characterized by intrauterine and mainly postnatal severe growth retardation.

Large hands



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PMID (PMCID)
7994336
MIXED_SAMPLE Infant, Newborn
[Physiopathological approach and antenatal diagnosis of diabetes mellitus insulin resistant: apropos of a case with leprechaunism].
Danan C, Amselem S, Dassieu G, Cohen R, Janaud JC.
Arch Pediatr. 1994;1(3):268-72.
Leprechaunism is characterized by severe intrauterine growth retardation, elfin-like face, relatively large hands, feet and genitalia and abnormal skin with hypertrichosis, acanthosis nigricans and low subcutaneous fat.