Hereditary leiomyomatosis and renal cell cancer

Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a hereditary cancer syndrome characterized by a predisposition to cutaneous and uterine leiomyomas and, in some families, to renal cell cancer.

Uterine leiomyoma

The presence of a leiomyoma of the uterus.


Total: 3

                       


(per page)
PMID (PMCID)
28700432
(5908258)
 FEMALE Adult
Novel Fumarate Hydratase Mutation in Siblings With Early Onset Uterine Leiomyomas and Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome.
Gunnala V, Pereira N, Irani M, Lilienthal D, Pirog EC, Soslow R, Caputo TA, Elias R, Kligman I, Rosenwaks Z.
Int J Gynecol Pathol. 2018;37(3):256-261.
Prompt diagnosis of hereditary leiomyomatosis renal cell cancer was made due to a high index of clinical suspicion based on early onset disease and familial clustering as well as characteristic pathologic findings on uterine leiomyoma surgical specimen.
28700432
(5908258)
 FEMALE Adult
Novel Fumarate Hydratase Mutation in Siblings With Early Onset Uterine Leiomyomas and Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome.
Gunnala V, Pereira N, Irani M, Lilienthal D, Pirog EC, Soslow R, Caputo TA, Elias R, Kligman I, Rosenwaks Z.
Int J Gynecol Pathol. 2018;37(3):256-261.
Timely diagnosis not only allowed for genetic counseling and renal cancer surveillance, but also for fertility counseling given the increased morbidity associated with uterine leiomyoma due to hereditary leiomyomatosis and renal cell cancer syndrome.
26990333
 MALE Adult
Piloleiomyomas in multiple cutaneous and uterine leiomyoma syndrome (hereditary leiomyomatosis and renal cell cancer or Reed syndrome).
Rieder E, Shvartsbeyn M, Meehan SA.
Dermatol Online J. 2015;21(12):.
Multiple cutaneous and uterine leiomyoma (MCL), or Reed syndrome is an uncommon condition that includes cutaneous piloleiomyomas and internal neoplasms of the uterus and kidney.