Thrombotic thrombocytopenic purpura

Thrombotic thrombocytopenic purpura (TTP) is an aggressive and life-threatening form of thrombotic microangiopathy (TMA; see this term) characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and organ failure of variable severity and is comprised of congenital TTP and acquired TTP (see these terms).

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PMID (PMCID)
18843079
MALE Middle Aged
Thrombotic thrombocytopenic purpura: a true haematological emergency.
Bedi N.
Emerg Med J. 2008;25(10):701-2.
Those that do exist, however, can prove devastatingly fatal if left untreated and a case is presented of one such possible diagnosis, thrombotic thrombocytopenic purpura, which falls into the remit of many possible presenting conditions.