Chondrosarcoma

Chondrosarcoma is a malignant bone tumor arising from cartilaginous tissue, most frequently occuring at the ends of the femur and tibia, the proximal end of the humerus and the pelvis; and presenting with a palpable mass and progressive pain. Chondrosarcoma is usually slow growing at low histological grades and can be well managed by intralesional curettage or en-block wide resection.

Multiple exostoses

Presence of more than one exostosis. An exostosis is a benign growth the projects outward from the bone surface. It is capped by cartilage, and arises from a bone that develops from cartilage.


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PMID (PMCID)
24762849
 MALE
Ewing sarcoma superimposed on a previous osteochondroma in multiple osteochondromatosis.
Marrero Barrera PA, Marrero Ortiz PV.
Orthopedics. 2014;37(4):e403-6.
It has been reported that patients with hereditary multiple exostoses (called multiple osteochondromatosis by the World Health Organization) are at increased risk for malignant transformation of osteochondromas to secondary chondrosarcomas.
17298471
 MALE Middle Aged
Histological diagnosis of spinal chondrosarcoma by endobronchial ultrasound-guided transbronchial needle aspiration.
Nakajima T, Yasufuku K, Suzuki M, Sekine Y, Shibuya K, Hiroshima K, Fujisawa T.
Respirology. 2007;12(2):308-10.
A very rare case of spinal chondrosarcoma due to hereditary multiple exostoses successfully diagnosed by endobronchial ultrasound-guided transbronchial needle aspiration and by immunohistochemistry with genetic analysis is reported.
15468904
 MALE Adult
[Three patients with hereditary multiple exostoses and malignant degeneration of an osteochondroma located in the pelvis].
Ham SJ, Heeg M, van Horn JR.
Ned Tijdschr Geneeskd. 2004;148(35):1732-8.
In three male patients with hereditary multiple exostoses (HME), aged 50, 29 and 31 years, peripheral low-grade chondrosarcoma in the pelvic region led to swelling or pain.
11289764
 FEMALE Middle Aged
Successful removal of a giant recurrent chondrosarcoma of the thoracic wall in a patient with hereditary multiple exostoses.
Rupprecht H, Spriewald BM, Hoffmann AR.
Eur J Surg Oncol. 2001;27(2):216-7.
Successful removal of a giant recurrent chondrosarcoma of the thoracic wall in a patient with hereditary multiple exostoses.
2290144
 MALE Adult
[Intrathoracic chondrosarcoma arising at a rib in a patient with multiple exostoses].
Fabaron F, Vandermarcq P, Pascard JP, Defaux F, Azais O, Barret D, Drouineau J, Gasquet C.
J Radiol. 1990;71(12):657-62.
[Intrathoracic chondrosarcoma arising at a rib in a patient with multiple exostoses].