Cold agglutinin disease

Cold agglutinin disease is a type of autoimmune hemolytic anemia (see this term) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30°C).

Hemolytic anemia

A type of anemia caused by premature destruction of red blood cells (hemolysis).


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PMID (PMCID)
30197053
 MALE Middle Aged
[Digital necrosis revealing cold agglutinin disease: Treatment with rituximab].
Klejtman T, Garel B, Senet P, Tribout L, Bachmeyer C, Barbaud A, Monfort JB.
Ann Dermatol Venereol. 2018;145(12):761-764.
Cold agglutinin disease is a rare type of auto-immune hemolytic anemia.
12888170
 MIXED_SAMPLE Middle Aged
[Rituximab in cold agglutinin disease].
Camou F, Viallard JF, Pellegrin JL.
Rev Med Interne. 2003;24(8):501-4.
Cold agglutinin disease is a chronic auto-immune hemolytic anemia related to a lymphoproliferative disorder with a degenerative potential and no codified treatment.
11235130
 MALE
[Systemic inflammatory response syndrome triggered by necrotizing cholecystitis after treatment of underlying low titer cold agglutinin disease].
Nagahama M, Kagawa H, Ozaki Y, Onishi S, Ishida T, Nomura S, Fukuhara S.
Rinsho Ketsueki. 2001;42(1):23-9.
In April 1996, a 77-year-old man initially presented with fever, rash and polyarthralgia, and was diagnosed as having low titer cold agglutinin disease with acute hemolytic anemia.
8890592
 FEMALE Adult
[Mycoplasma infection and hemolytic anemia].
Nasu K.
Nihon Rinsho. 1996;54(9):2545-9.
Hemolytic anemia due to cold agglutinin disease is a known complication of Mycoplasma pneumoniae infection but is rarely observed.
2316001
 MALE Middle Aged
Autoimmune hemolytic anemia caused by a cold agglutinin with a new specificity (anti-Ju).
Gottsche B, Salama A, Mueller-Eckhardt C.
Transfusion. 1990;30(3):261-2.
A cold autoantibody detected in the serum of a patient with chronic idiopathic cold agglutinin disease and hemolytic anemia is described.
3367618
 FEMALE
[Cold agglutinin disease--initial description in erythroblastosis and polycythemia vera].
Geissler RG, Kobberling J.
Klin Wochenschr. 1988;66(6):261-3.
The cold agglutinin disease is a hemolytic anemia induced by antibodies.