Cold agglutinin disease

Cold agglutinin disease is a type of autoimmune hemolytic anemia (see this term) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30°C).

Leukemia

A cancer of the blood and bone marrow characterized by an abnormal proliferation of leukocytes.


Total: 6

                       


(per page)
PMID (PMCID)
27099738
(4831394)
 OTHER
Acrocyanosis revealing chronic lymphocytic leukemia.
Lesesve JF.
Clin Case Rep. 2016;4(4):404-5.
Cold agglutinin disease arising in the context of chronic lymphocytic leukemia can misdiagnose a warm autoimmune hemolytic anemia.
12384446
 MALE Middle Aged
Chronic lymphocytic leukemia preceded by cold agglutinin disease: intraclonal immunoglobulin light-chain diversity in V(H)4-34 expressing single leukemic B cells.
Ruzickova S, Pruss A, Odendahl M, Wolbart K, Burmester GR, Scholze J, Dorner T, Hansen A.
Blood. 2002;100(9):3419-22.
Chronic lymphocytic leukemia preceded by cold agglutinin disease: intraclonal immunoglobulin light-chain diversity in V(H)4-34 expressing single leukemic B cells.
7526015
 MALE Middle Aged
[Chronic cold agglutinin disease accompanied with an increase of CD20+/CD5+ cells; a case report].
Notoya A, Hirayama S, Takano H, Koizumi K, Satoh N, Yasukouchi T, Sawada K, Koike T.
Rinsho Ketsueki. 1994;35(9):881-5.
At this point we diagnosed cold agglutinin disease (CAD) because there was no evidence of lymphoma, and the absolute number of peripheral blood lymphocytes was lower than the criteria of chronic lymphocytic leukemia (CLL) proposed by the International Workshop (1989).
8296193
 FEMALE Middle Aged
[Treatment of severe idiopathic cold-agglutinin diseases using interferon-alpha 2b].
Rordorf R, Barth A, Nydegger U, Tobler A.
Schweiz Med Wochenschr. 1994;124(1-2):56-61.
Based on in vitro evidence, primary cold agglutinin disease can be considered as a low grade malignant lymphoproliferative disorder in which interferon-alpha has been shown to be an effective therapeutic agent, at least in forms such as hairy cell leukemia.
6807086
 MALE Adult
B-cell neoplasms with homogeneous cold-reacting antibodies (cold agglutinins).
Crisp D, Pruzanski W.
Am J Med. 1982;72(6):915-22.
Among 78 patients with persistent cold agglutinins, 31 had lymphoma, 13 had macroglobulinemia of Waldenstrom, six had chronic lymphocytic leukemia and 28 had chronic cold agglutinin disease.
6807086
 MALE Adult
B-cell neoplasms with homogeneous cold-reacting antibodies (cold agglutinins).
Crisp D, Pruzanski W.
Am J Med. 1982;72(6):915-22.
Survival time from diagnosis was on average two years in lymphoma, two and a half years in Waldenstrom's macroglobulinemia, more than six years in chronic lymphocytic leukemia and more than five years in chronic cold agglutinin disease.