Cold agglutinin disease

Cold agglutinin disease is a type of autoimmune hemolytic anemia (see this term) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30°C).

Acute kidney injury

Sudden loss of renal function, as manifested by decreased urine production, and a rise in serum creatinine or blood urea nitrogen concentration (azotemia).


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(per page)
PMID (PMCID)
29984743
(6287995)
 MALE
Acute Kidney Injury by Renal Hemosiderosis Secondary to Primary Cold Agglutinin Disease Associated with an Excessive Alcohol Intake.
Imafuku A, Yamamoto G, Takemura K, Hasegawa E, Sawa N, Kawada M, Sekine A, Hoshino J, Takaichi K, Fujii T, Ohashi K, Ubara Y.
Intern Med. 2018;57(22):3261-3265.
Patients with cold agglutinin disease (CAD) have relatively mild hemolysis, and acute kidney injury (AKI) due to renal hemosiderosis has not been reported.
29984743
(6287995)
 MALE
Acute Kidney Injury by Renal Hemosiderosis Secondary to Primary Cold Agglutinin Disease Associated with an Excessive Alcohol Intake.
Imafuku A, Yamamoto G, Takemura K, Hasegawa E, Sawa N, Kawada M, Sekine A, Hoshino J, Takaichi K, Fujii T, Ohashi K, Ubara Y.
Intern Med. 2018;57(22):3261-3265.
Acute Kidney Injury by Renal Hemosiderosis Secondary to Primary Cold Agglutinin Disease Associated with an Excessive Alcohol Intake.