Cold agglutinin disease

Cold agglutinin disease is a type of autoimmune hemolytic anemia (see this term) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30°C).

Hypothermia

Reduced body temperature due to failed thermoregulation.


Total: 10

                       


(per page)
PMID (PMCID)
29885944
 MALE
Cold agglutinin disease complicating management of aortic dissection.
Bras J, Uminski K, Ponnampalam A.
Transfus Apher Sci. 2018;57(2):236-238.
Plasma exchange alone may be sufficient in preparing patients with cold agglutinin disease for procedures requiring significant hypothermia when the delayed onset of action of alternative therapies is not acceptable.
28698413
 FEMALE
[Aortic Stenosis Combined with Cold Agglutinin Disease].
Yu Z, Minakawa M, Aoki T, Kondo N, Daitoku K, Suzuki Y, Fukuda I.
Kyobu Geka. 2017;70(7):490-492.
Cardiac surgery on a patient with cold agglutinin disease is high risk for thromboembolism due to hypothermia perioperative.
19378854
 MALE
[Pre-operative care for cardiac surgery patients with cold antibody disorder, cryoglobulinaemia and cryofibrinogenemia].
Gumulec J, Brat R, Kolek M, Chrastecky B, Koristka M, Cermakova Z, Novakova L, Sachova L, Chasakova K, Ranochova A, Ryzi M, Navratova P, Zuchnicka J, Bodzasova C, Plonkova H, Slezak P.
Vnitr Lek. 2009;55(3):236-41.
We present an example of a patient with confirmed cold agglutinin disease who underwent cardiac surgery in hypothermia to illustrate a known fact that, when exposed to cold, cold agglutinins induce haemolysis of erythrocytes and that cryoglobulins and cryofibrinogens may, upon exposition to cold during a surgery under hypothermia, precipitate or gelify and thus increase plasma viscosity and damage microcirculation.
19378854
 MALE
[Pre-operative care for cardiac surgery patients with cold antibody disorder, cryoglobulinaemia and cryofibrinogenemia].
Gumulec J, Brat R, Kolek M, Chrastecky B, Koristka M, Cermakova Z, Novakova L, Sachova L, Chasakova K, Ranochova A, Ryzi M, Navratova P, Zuchnicka J, Bodzasova C, Plonkova H, Slezak P.
Vnitr Lek. 2009;55(3):236-41.
We present an example of a patient with confirmed cold agglutinin disease who underwent cardiac surgery in hypothermia to illustrate a known fact that, when exposed to cold, cold agglutinins induce haemolysis of erythrocytes and that cryoglobulins and cryofibrinogens may, upon exposition to cold during a surgery under hypothermia, precipitate or gelify and thus increase plasma viscosity and damage microcirculation.
19378854
 MALE
[Pre-operative care for cardiac surgery patients with cold antibody disorder, cryoglobulinaemia and cryofibrinogenemia].
Gumulec J, Brat R, Kolek M, Chrastecky B, Koristka M, Cermakova Z, Novakova L, Sachova L, Chasakova K, Ranochova A, Ryzi M, Navratova P, Zuchnicka J, Bodzasova C, Plonkova H, Slezak P.
Vnitr Lek. 2009;55(3):236-41.
Detailed immunological and haematological investigations in all patients awaiting cardiac surgery with a risk of developing hypothermia is not advantageous considering the low number of patients with clinical and laboratory signs of cold agglutinin disease, autoimmune haemolytic anaemia or paroxysmal cold haemoglobinuria and considering that these investigations, in addition, might not detect cryoglobulinaemia and cryofibrinogenemia.
18649642
 MALE
[Perioperative management for cardiovascular operations in two patients with cold agglutinin disease].
Itagaki T, Kikura M, Ishida C, Katoh H, Oikawa F, Iwamoto T, Hirano K, Sato S.
Masui. 2008;57(7):869-73.
Therefore, special consideration is required in patients with cold agglutinin disease (CAD) undergoing cardiovascular surgery requiring hypothermia.
16704598
 MALE Middle Aged
Major colorectal surgery in a patient with cold agglutinin disease.
Young S, Haldane G.
Anaesthesia. 2006;61(6):593-6.
Peri-operative hypothermia is common in all patients and may be associated with significant morbidity, but is potentially catastrophic in a patient suffering from cold agglutinin disease.
8222845
 MALE
Cardiac operation without hypothermia for the patient with cold agglutinin.
Aoki A, Kay GL, Zubiate P, Ruggio J, Kay JH.
Chest. 1993;104(5):1627-9.
Hypothermia is not part of this technique; thus, the danger of hypothermia can be avoided in the patient with cold agglutinin disease without compromising myocardial protection.
8222845
 MALE
Cardiac operation without hypothermia for the patient with cold agglutinin.
Aoki A, Kay GL, Zubiate P, Ruggio J, Kay JH.
Chest. 1993;104(5):1627-9.
Hypothermia is not part of this technique; thus, the danger of hypothermia can be avoided in the patient with cold agglutinin disease without compromising myocardial protection.
7120502
 FEMALE
Intraoperative hypothermia in a patient with cold agglutinin disease.
Guena L, Addei KA.
J Natl Med Assoc. 1982;74(7):691-2.
A patient with cold agglutinin disease developed significant hemolysis after surgery because of intraoperative hypothermia.