Cold agglutinin disease

Cold agglutinin disease is a type of autoimmune hemolytic anemia (see this term) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30°C).

Hyperbilirubinemia

An increased amount of bilirubin in the blood.


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PMID (PMCID)
28133289
MALE Middle Aged
[Radical Operation Performed on a Gastric Cancer Patient with Cold Agglutinin Disease - A Case Report].
Wakasa Y, Wajima N, Akasaka H, Muroya T, Okano K, Yoshida E, Hakamada K.
Gan To Kagaku Ryoho. 2016;43(12):2262-2264.
The preoperative laboratory tests indicated anemia, hyperbilirubinemia, hemagglutinin reaction, and a markedly high cold agglutinin titer; thus, we diagnosed the patient with cold agglutinin disease(CAD).