Cold agglutinin disease

Cold agglutinin disease is a type of autoimmune hemolytic anemia (see this term) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30°C).

Flushing

Recurrent episodes of redness of the skin together with a sensation of warmth or burning of the affected areas of skin.


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(per page)
PMID (PMCID)
2787974
MALE
Detection of cold hemagglutination in a blood cardioplegia unit before systemic cooling of a patient with unsuspected cold agglutinin disease.
Dake SB, Johnston MF, Brueggeman P, Barner HB.
Ann Thorac Surg. 1989;47(6):914-5.
A case is described in which hemagglutination occurred intraoperatively in cold blood flushed through the blood cardioplegia delivery system from a patient with unsuspected cold agglutinin disease.