Cystic fibrosis

Cystic fibrosis (CF) is a genetic disorder characterized by the production of sweat with a high salt content and mucus secretions with an abnormal viscosity.

Osteoporosis

Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility. According to the WHO criteria, osteoporosis is defined as a BMD that lies 2.5 standard deviations or more below the average value for young healthy adults (a T-score below -2.5 SD).


Total: 7

                       


(per page)
PMID (PMCID)
25270323
(4197343)
 MALE Adult
Rib plating of acute and sub-acute non-union rib fractures in an adult with cystic fibrosis: a case report.
Dean NC, Van Boerum DH, Liou TG.
BMC Res Notes. 2014;7:681.
Rib fractures associated with osteoporosis have been reported to occur ten times more frequently in adults with cystic fibrosis.
22461833
 OTHER
Hypervitaminosis D: case report of pediatric osteoporosis secondary to cystic fibrosis.
Cialdella P, Carella F.
Clin Cases Miner Bone Metab. 2011;8(3):66-8.
We took into account the clinical case of a child who right from the age of seven years has presented joint pain.The little girl was diagnosed with osteopenia taken with therapy of calcium and vitamin D; after few years despite treatment nephrocalcinosis and osteoporosis take over.It was examined a cohort of patients with cystic fibrosis of the southern Italy, 24 patients aged between 12 and 44 years, 12 females and 12 males with BMD assessment methods like dual energy X-rays (DXA) and calcaneal ultrasound densitometry in a few cases, ultrasonography was used jointly.From this case study we tried to establish the relationship between cystic fibrosis and osteoporosis etiopathogenetic, the adoptive therapy and the impact of therapies on patients.It was concluded that, given the high number of unrecognized patients with impaired bone mineralization, we must implement and integrate a more aggressive treatment with bisphosphonates and prevention programs that can combat the lifestyle and new eating habits of our young people that facilitate the loss of bone mass.
22461833
 OTHER
Hypervitaminosis D: case report of pediatric osteoporosis secondary to cystic fibrosis.
Cialdella P, Carella F.
Clin Cases Miner Bone Metab. 2011;8(3):66-8.
We took into account the clinical case of a child who right from the age of seven years has presented joint pain.The little girl was diagnosed with osteopenia taken with therapy of calcium and vitamin D; after few years despite treatment nephrocalcinosis and osteoporosis take over.It was examined a cohort of patients with cystic fibrosis of the southern Italy, 24 patients aged between 12 and 44 years, 12 females and 12 males with BMD assessment methods like dual energy X-rays (DXA) and calcaneal ultrasound densitometry in a few cases, ultrasonography was used jointly.From this case study we tried to establish the relationship between cystic fibrosis and osteoporosis etiopathogenetic, the adoptive therapy and the impact of therapies on patients.It was concluded that, given the high number of unrecognized patients with impaired bone mineralization, we must implement and integrate a more aggressive treatment with bisphosphonates and prevention programs that can combat the lifestyle and new eating habits of our young people that facilitate the loss of bone mass.
22461833
 OTHER
Hypervitaminosis D: case report of pediatric osteoporosis secondary to cystic fibrosis.
Cialdella P, Carella F.
Clin Cases Miner Bone Metab. 2011;8(3):66-8.
We took into account the clinical case of a child who right from the age of seven years has presented joint pain.The little girl was diagnosed with osteopenia taken with therapy of calcium and vitamin D; after few years despite treatment nephrocalcinosis and osteoporosis take over.It was examined a cohort of patients with cystic fibrosis of the southern Italy, 24 patients aged between 12 and 44 years, 12 females and 12 males with BMD assessment methods like dual energy X-rays (DXA) and calcaneal ultrasound densitometry in a few cases, ultrasonography was used jointly.From this case study we tried to establish the relationship between cystic fibrosis and osteoporosis etiopathogenetic, the adoptive therapy and the impact of therapies on patients.It was concluded that, given the high number of unrecognized patients with impaired bone mineralization, we must implement and integrate a more aggressive treatment with bisphosphonates and prevention programs that can combat the lifestyle and new eating habits of our young people that facilitate the loss of bone mass.
22461833
 OTHER
Hypervitaminosis D: case report of pediatric osteoporosis secondary to cystic fibrosis.
Cialdella P, Carella F.
Clin Cases Miner Bone Metab. 2011;8(3):66-8.
We took into account the clinical case of a child who right from the age of seven years has presented joint pain.The little girl was diagnosed with osteopenia taken with therapy of calcium and vitamin D; after few years despite treatment nephrocalcinosis and osteoporosis take over.It was examined a cohort of patients with cystic fibrosis of the southern Italy, 24 patients aged between 12 and 44 years, 12 females and 12 males with BMD assessment methods like dual energy X-rays (DXA) and calcaneal ultrasound densitometry in a few cases, ultrasonography was used jointly.From this case study we tried to establish the relationship between cystic fibrosis and osteoporosis etiopathogenetic, the adoptive therapy and the impact of therapies on patients.It was concluded that, given the high number of unrecognized patients with impaired bone mineralization, we must implement and integrate a more aggressive treatment with bisphosphonates and prevention programs that can combat the lifestyle and new eating habits of our young people that facilitate the loss of bone mass.
22461833
 OTHER
Hypervitaminosis D: case report of pediatric osteoporosis secondary to cystic fibrosis.
Cialdella P, Carella F.
Clin Cases Miner Bone Metab. 2011;8(3):66-8.
Hypervitaminosis D: case report of pediatric osteoporosis secondary to cystic fibrosis.
10515433
 MALE Adult
Hip fracture and bone histomorphometry in a young adult with cystic fibrosis.
Haworth CS, Freemont AJ, Webb AK, Dodd ME, Selby PL, Mawer EB, Adams JE.
Eur Respir J. 1999;14(2):478-9.
Osteoporosis is thought to be a common complication of cystic fibrosis.