Cystic fibrosis

Cystic fibrosis (CF) is a genetic disorder characterized by the production of sweat with a high salt content and mucus secretions with an abnormal viscosity.

Chronic infection

Presence of a protracted or persistent infection by a pathogen potentially related to an underlying abnormality of the immune system that is not able to clear the infection.


Total: 13

                       


(per page)
PMID (PMCID)
30026964
(6050648)
 OTHER
Acute retinal vein occlusion and cystic fibrosis.
Starr MR, Norby SM, Scott JP, Bakri SJ.
Int J Retina Vitreous. 2018;4:26.
Elevated fibrinogen levels in these patients may not be due to chronic infections, but inherent to the cystic fibrosis.
30026964
(6050648)
 OTHER
Acute retinal vein occlusion and cystic fibrosis.
Starr MR, Norby SM, Scott JP, Bakri SJ.
Int J Retina Vitreous. 2018;4:26.
These reports hypothesized that either elevated fibrinogen levels due to chronic infections or elevated homocysteine levels have predisposed patients with cystic fibrosis to develop retinal vein occlusions.
30212579
(6136817)
 MALE Middle Aged
Great phenotypic and genetic variation among successive chronic Pseudomonas aeruginosa from a cystic fibrosis patient.
Lozano C, Azcona-Gutierrez JM, Van Bambeke F, Saenz Y.
PLoS One. 2018;13(9):e0204167.
Relevant biological determinants in P. aeruginosa successively isolated from a cystic fibrosis (CF) patient were analyzed in this work to gain insight into P. aeruginosa heterogeneity during chronic infection.
28491333
(5405907)
 OTHER
Burkholderia cepacia complex and limited cutaneous vasculitis in patients with cystic fibrosis: a case series.
Kayria M, Chris O, Dhasmana DJ, Nilesh M, Hodson ME, Khin G, Diana B, Simmonds NJ.
JRSM Open. 2017;8(4):2054270417692732.
There is a high association of reactive skin presentations, mainly limited cutaneous vasculitis in patients with cystic fibrosis and Burkholderia cepcia complex chronic infection.
27552791
 MALE
Pulmonary exacerbation due to colistin-resistant Stenotrophomonas maltophilia in a Bulgarian cystic fibrosis patient.
Stoyanova GP, Strateva TV, Atanasova ST, Miteva DS, Papochieva VE, Perenovska PI.
Folia Med (Plovdiv). 2016;58(2):136-40.
In patients with cystic fibrosis (CF) lung damage secondary to chronic infection is the main cause of death.
27018049
(4809030)
 MIXED_SAMPLE Child
Two case reports of the successful eradication of new isolates of Burkholderia cepacia complex in children with cystic fibrosis.
Kitt H, Lenney W, Gilchrist FJ.
BMC Pharmacol Toxicol. 2016;17:14.
Chronic infection with Burkholderia cepacia complex (BCC) has a detrimental effect on morbidity and mortality for patients with cystic fibrosis (CF).
26445233
(4596362)
 MALE Child
A case of failed eradication of cystic fibrosis-related sinus colonisation by Pseudomonas aeruginosa.
Linnane B, Kearse L, O'Connell NH, Fenton J, Kiernan MG, Dunne CP.
BMC Pulm Med. 2015;15:114.
A 12 year old Irish male paediatric cystic fibrosis patient experienced intermittent culturing of P. aeruginosa from the oropharyngeal region, indicating chronic infection of the sinuses despite absence of symptoms, retaining good lung function, and normal bronchoscopy and bronchoalveolar lavage.
26482905
(4612410)
 MIXED_SAMPLE Infant
Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients.
Marvig RL, Dolce D, Sommer LM, Petersen B, Ciofu O, Campana S, Molin S, Taccetti G, Johansen HK.
BMC Microbiol. 2015;15:218.
Chronic infection with Pseudomonas aeruginosa is a major cause of morbidity and mortality in cystic fibrosis (CF) patients, and a more complete understanding of P. aeruginosa within-host genomic evolution, transmission, and population genomics may provide a basis for improving intervention strategies.
18356119
 FEMALE Adult
Successful treatment of cepacia syndrome with combination nebulised and intravenous antibiotic therapy.
Weidmann A, Webb AK, Dodd ME, Jones AM.
J Cyst Fibros. 2008;7(5):409-11.
We report the case of successful treatment of a 31-year-old lady with cystic fibrosis and an en-bloc liver-pancreas transplant, who developed cepacia syndrome on a background of chronic infection with the ET12 epidemic strain of Burkholderia cenocepacia.
18728207
 MALE Middle Aged
Transmission of Pseudomonas aeruginosa epidemic strain from a patient with cystic fibrosis to a pet cat.
Mohan K, Fothergill JL, Storrar J, Ledson MJ, Winstanley C, Walshaw MJ.
Thorax. 2008;63(9):839-40.
Chronic infection with Pseudomonas aeruginosa is common in cystic fibrosis (CF) and certain strains are more transmissible and virulent than others.
7535673
 MIXED_SAMPLE Infant
Comparison by extended ribotyping of Pseudomonas cepacia isolated from cystic fibrosis patients with acute and chronic infections.
Rozee KR, Haase D, Macdonald NE, Johnson WM.
Diagn Microbiol Infect Dis. 1994;20(4):181-6.
Comparison by extended ribotyping of Pseudomonas cepacia isolated from cystic fibrosis patients with acute and chronic infections.
2076629
 FEMALE Adult
Diabetes secondary to cystic fibrosis: an increasing clinical problem.
Nettles AT, Weinhandl J.
Diabetes Educ. 1990;16(6):478-82.
The challenge to diabetes educators in managing these patients is to incorporate basic diabetes treatment into a life-style that includes chronic infections, variable food intakes, multiple demands on time for self-care procedures, and the psychosocial problems posed by cystic fibrosis.
7284907
 MALE Child
Pulmonary resection in cystic fibrosis: a case report.
Gelfand ET, Mehta H, Callaghan JC.
Can J Surg. 1981;24(5):458-60.
An 8-year-old boy with cystic fibrosis and a chronic infection of the right lung with abscess formation underwent pulmonary resection after 1 week of antibiotic therapy with tobramycin, ticarcillin and cloxacillin, and physiotherapy.