Neuroblastoma

Neuroblastoma is a malignant tumor of neural crest cells, the cells that give rise to the sympathetic nervous system, which is observed in children.

Renal insufficiency

A reduction in the level of performance of the kidneys in areas of function comprising the concentration of urine, removal of wastes, the maintenance of electrolyte balance, homeostasis of blood pressure, and calcium metabolism.


Total: 2

                       


(per page)
PMID (PMCID)
21941489
(3177796)
 OTHER
Neuroblastoma presenting with acute kidney injury, hyponatremic-hypertensive-like syndrome and nephrotic proteinuria in a 10-month-old child.
Poggi GM, Fognani G, Cuzzubbo D, Liguori A, Resti M, Pela I.
Case Rep Oncol. 2011;4(2):400-5.
Herein we describe a 10-month-old child with neuroblastoma presenting with a complex clinical picture characterized by acute kidney injury manifested by renal insufficiency and signs and symptoms of tubulointerstitial damage, with polyuria, polydipsia, glucosuria, aminoaciduria and hypochloremic metabolic alkalosis, and of glomerular damage with heavy proteinuria.
15719254
 MIXED_SAMPLE
Retinoic acid may increase the risk of bone marrow transplant nephropathy.
Haysom L, Ziegler DS, Cohn RJ, Rosenberg AR, Carroll SL, Kainer G.
Pediatr Nephrol. 2005;20(4):534-8.
They were both treated for stage IV neuroblastoma with chemotherapy, bone marrow transplant (BMT) conditioning that included total body irradiation and RA therapy after BMT, although the patient in case 1 had established renal insufficiency prior to the commencement of RA.