Neuroblastoma

Neuroblastoma is a malignant tumor of neural crest cells, the cells that give rise to the sympathetic nervous system, which is observed in children.

Round face

The facial appearance is more circular than usual as viewed from the front.


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PMID (PMCID)
17542878
 FEMALE Child
Hypohidrotic ectodermal dysplasia and intrathoracic neuroblastoma.
Buoni S, Zannolli R, Macucci F, Molinelli M, Viviano M, Cuccia A, Hayek J, Volterrani L, de Santi MM, Miracco C, Fois A.
Pediatr Dermatol. 2007;24(3):267-71.
We report a 6-year-old girl with a subtle form of hypohidrotic ectodermal dysplasia and a phenotype consisting of curly hair, a round face, a stocky build, and obesity, which was associated with intrathoracic neuroblastoma.