Neuroblastoma

Neuroblastoma is a malignant tumor of neural crest cells, the cells that give rise to the sympathetic nervous system, which is observed in children.

Aniridia

Abnormality of the iris characterized by, typically bilateral, complete or partial iris hypoplasia. The phenotype ranges from mild defects of anterior iris stroma only to almost complete absence of the iris.


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PMID (PMCID)
2922225
 MALE Infant, Newborn
The association of congenital neuroblastoma and congenital heart disease. Is there a common embryologic basis?
Bellah R, D'Andrea A, Darillis E, Fellows KE.
Pediatr Radiol. 1989;19(2):119-21.
Several authors have reported an association between neuroblastoma and congenital heart disease; others contend that, unlike specific well-known associations between malignancy and congenital defects (Wilm's tumor and aniridia, leukemia and Down's syndrome), no real relationship exists.