Neuroblastoma

Neuroblastoma is a malignant tumor of neural crest cells, the cells that give rise to the sympathetic nervous system, which is observed in children.

Autoimmunity

The occurrence of an immune reaction against the organism's own cells or tissues.


Total: 1

                      


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PMID (PMCID)
22529275
FEMALE Child
Excessive blinking and ataxia in a child with occult neuroblastoma and voltage-gated potassium channel antibodies.
Allen NM, McKeon A, O'Rourke DJ, O'Meara A, King MD.
Pediatrics. 2012;129(5):e1348-52.
Although voltage-gated potassium channel complex autoimmunity has not been described previously in the setting of neuroblastoma, it is associated with a spectrum of paraneoplastic neurologic manifestations in adults, including peripheral nerve hyperexcitability disorders.