Osteosarcoma

Osteosarcoma is a primary malignant tumour of the skeleton characterised by the direct formation of immature bone or osteoid tissue by the tumour cells.

Hypodontia

A developmental anomaly characterized by a reduced number of teeth, whereby up to 6 teeth are missing.


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PMID (PMCID)
3856492
 MIXED_SAMPLE Child
Non-dermatological complications and genetic aspects of the Rothmund-Thomson syndrome.
Starr DG, McClure JP, Connor JM.
Clin Genet. 1985;27(1):102-4.
We report two new cases of Rothmund-Thomson syndrome which emphasize the less well-known non-dermatological complications, namely: hypodontia, soft tissue contractures, proportionate short stature, hypogonadism, anaemia and osteogenic sarcoma.