Cholangiocarcinoma

Cholangiocarcinoma (CCA) is a biliary tract cancer (BTC, see this term) originating in the epithelium of the biliary tree, either intra or extra hepatic.

Cirrhosis

A chronic disorder of the liver in which liver tissue becomes scarred and is partially replaced by regenerative nodules and fibrotic tissue resulting in loss of liver function.


Total: 35

                       


(per page)
PMID (PMCID)
28840045
(5559919)
 OTHER
Hemoperitoneum Secondary to Spontaneous Rupture of a Retroperitoneal Varix.
Eichele DD.
Case Reports Hepatol. 2017;2017:1829676.
We present a unique case of a 56-year-old female with cirrhosis secondary to primary sclerosing cholangitis who presented with acute abdominal pain and hypovolemic shock prior to a cardiac arrest following a ruptured retroperitoneal varix without prior esophageal varices and a newly identified intrahepatic cholangiocarcinoma.
24849871
 OTHER
Intrahepatic cholangiocarcinoma in a worker at an offset color proof-printing company: An autopsy case report.
Tomimaru Y, Kobayashi S, Wada H, Hama N, Kawamoto K, Eguchi H, Kira T, Morii E, Doki Y, Mori M, Nagano H.
Hepatol Res. 2015;45(4):488-93.
A CT examination showed liver cirrhosis without recurrence of the cholangiocarcinoma.
25184033
(4149740)
 OTHER
Synchronous hepatocellular carcinoma and cholangiocarcinoma in a patient transplanted for cryptogenic cirrhosis.
Geramizadeh B, Gity R, Bahraini A, Malek-Hosseini SA.
Int J Organ Transplant Med. 2014;5(3):125-8.
Synchronous hepatocellular carcinoma and cholangiocarcinoma in a patient transplanted for cryptogenic cirrhosis.
24313990
(4029323)
 FEMALE
Synchronous development of intrahepatic cholangiocarcinoma and hepatocellular carcinoma in different sites of the liver with chronic B-viral hepatitis: two case reports.
Jung KS, Chun KH, Choi GH, Jeon HM, Shin HS, Park YN, Park JY.
BMC Res Notes. 2013;6:520.
In literature review, there have been only 35 reported cases of synchronous hepatocellular carcinoma and intrahepatic cholangiocarcinoma, and most of these tumors developed in patients with hepatitis C-related liver cirrhosis.
21528069
 MALE
Intraductal papillary neoplasm of the bile duct in liver cirrhosis with hepatocellular carcinoma.
Xu J, Sato Y, Harada K, Yoneda N, Ueda T, Kawashima A, Akishiooi , Nakanuma Y.
World J Gastroenterol. 2011;17(14):1923-6.
It seems possible in this case that hepatic progenitor cells located in reactive bile ductules in liver cirrhosis may have been responsible for the development of the cholangiocarcinoma and HCC, and that the former could have spread in the intrahepatic bile ducts and eventually formed grossly visible IPNB.
21843735
 FEMALE Child
Liver transplantation in a 7-month-old girl with Caroli's disease.
Kim RD, Book L, Haafiz A, Schwartz JJ, Sorensen JB, Gonzalez-Peralta RP.
J Pediatr Surg. 2011;46(8):1638-41.
Patients with recurrent complications or cirrhosis may die because of recurrent infection, portal hypertension, liver failure, or cholangiocarcinoma.
20934950
(2999407)
 FEMALE
Primary hepatoid carcinoma of the biliary tree: a radiologic mimicker of Klatskin-type tumor.
Abdullah A, Jenkins-Mosure K, Lewis T, Patel Y, Strobel S, Pepe L.
Cancer Imaging. 2010;10:198-201.
We report a unique case in the literature of a 67-year-old Caucasian female who presented with obstructive jaundice due to an obstructing mass seen at the common hepatic duct on imaging with no preceding history of cirrhosis and increased serum 945-fetoprotein (AFP), in whom a differential diagnosis from cholangiocarcinoma in a non-cirrhotic liver was particularly difficult given the combination of tumor location and solitary nature.
20382595
 MALE Adult
Small-duct primary sclerosing cholangitis with hepatocellular carcinoma requiring liver transplantation.
Ali S, Shah V.
Hepatobiliary Pancreat Dis Int. 2010;9(2):208-12.
Small-duct PSC has a substantially better prognosis than the large-duct type, with less chance of developing cirrhosis and an equal risk for developing hepatocellular carcinoma, but no increased risk for developing cholangiocarcinoma.
19557545
 FEMALE Middle Aged
Autopsy case of Gaucher disease type I in a patient on enzyme replacement therapy. Comments on the dynamics of persistent storage process.
Hulkova H, Ledvinova J, Poupetova H, Kohout A, Malinova V, Elleder M.
J Inherit Metab Dis. 2009;32(4):551-9.
Autopsy revealed liver cholestatic cirrhosis and multifocal liver carcinoma with immunophenotype compatible with cholangiocarcinoma.
19100500
 FEMALE Middle Aged
Intrahepatic cholangiocarcinoma arising in chronic viral hepatitis-associated cirrhosis: two transplant cases.
Nart D, Ertan Y, Pala EE, Zeytunlu M, Kilic M, Yilmaz F.
Transplant Proc. 2008;40(10):3813-5.
Intrahepatic cholangiocarcinoma arising in chronic viral hepatitis-associated cirrhosis: two transplant cases.
18067645
 MALE Middle Aged
Lymphoepithelioma-like cholangiocarcinoma not associated with EBV.
Adachi S, Morimoto O, Kobayashi T.
Pathol Int. 2008;58(1):69-74.
Reported herein is an unusual case of intrahepatic cholangiocarcinoma with lymphoepithelioma-like appearance in a 64-year-old man who was found to have an intrahepatic mass without cirrhosis.
17701135
 MALE Middle Aged
Perihilar cholangiocarcinoma arising in hepatitis C virus-related liver cirrhosis with hepatocellular carcinoma.
Fujii T, Zen Y, Nakanuma Y.
J Gastroenterol. 2007;42(8):698-702.
Perihilar cholangiocarcinoma arising in hepatitis C virus-related liver cirrhosis with hepatocellular carcinoma.
17701135
 MALE Middle Aged
Perihilar cholangiocarcinoma arising in hepatitis C virus-related liver cirrhosis with hepatocellular carcinoma.
Fujii T, Zen Y, Nakanuma Y.
J Gastroenterol. 2007;42(8):698-702.
Hilar/perihilar cholangiocarcinoma arising in hepatitis C virus-related liver cirrhosis has rarely been reported.
16567920
 MALE Child
Caroli's disease.
Gupta AK, Gupta A, Bhardwaj VK, Chansoria M.
Indian J Pediatr. 2006;73(3):233-5.
Cholangitis liver, cirrhosis and cholangiocarcinoma are its potential complication.
16634969
 MALE Middle Aged
Combined hepatocellular carcinoma and cholangiocarcinoma with components of mucinous carcinoma arising in a cirrhotic liver.
Morita D, Kagata Y, Ogata S, Tsuda H, Hatsuse K, Mochizuki H, Matsubara O.
Pathol Int. 2006;56(4):222-6.
A rare autopsy case of combined hepatocellular and cholangiocarcinoma, occurring in a 54-year-old man with liver cirrhosis, is presented.
15347876
 MALE Child
Caroli's disease.
Karim AS.
Indian Pediatr. 2004;41(8):848-50.
Cholangitis, liver cirrhosis and cholangiocarcinoma are its potential complications.
12610331
 MALE
Advanced intrahepatic cholangiocarcinoma in hepatitis C virus-related decompensated cirrhosis: case report and review of the literature.
Polizos A, Kelekis N, Sinani C, Patsiaoura K, Papadamou G, Dalekos GN.
Eur J Gastroenterol Hepatol. 2003;15(3):331-4.
Advanced intrahepatic cholangiocarcinoma in hepatitis C virus-related decompensated cirrhosis: case report and review of the literature.
12169991
 FEMALE Adult
Association of primary sclerosing cholangitis, ulcerative colitis and coeliac disease in female siblings.
Habior A, Rawa T, Orlowska J, Sankowska M, Lewartowska A, Tilszer A, Pawlak J, Krawczyk M, Butruk E.
Eur J Gastroenterol Hepatol. 2002;14(7):787-91.
Although HLA DR4 was not found, there was a rapid progression of liver disease to cirrhosis and cholangiocarcinoma in one patient.
12434102
 MALE Middle Aged
[Cholangiocarcinoma developing in von Meyenburg complexes in haemochromatosis].
Wisniewski B, Tordjman G, Tran Van Nhieu J, Bettan L, Courillon-Mallet A.
Gastroenterol Clin Biol. 2002;26(10):922-4.
Patients with an association of genetic haemochromatosis and von Meyenburg complexes might have a predisposition to cholangiocarcinoma, even before cirrhosis occurs.
11981497
 MALE Adult
[Fibrous tissue(s): a key for lesion characterization in digestive diseases].
Regent D, Laurent V, Antunes L, Debelle L, Cannard L, Leclerc J, Beot S.
J Radiol. 2002;83(2 Pt 2):292-312.
Delayed enhancement of collagenic fibrous tissue during the late post-equilibrium phase is an essential complementary data in the characterization of many liver lesions: cirrhosis, cholangiocarcinoma, focal nodular hyperplasia, fibrous metastasis.