Small cell lung cancer

Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized by rapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure.

Proteinuria

Increased levels of protein in the urine.


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PMID (PMCID)
19343274
MALE Middle Aged
Proteinuria and proximal tubule lesions induced by an anti-integrin monoclonal antibody treatment: case report.
Gombos A, Izzedine H, Besse B, Massard C, Brocheriou I, Bahleda R, Soria JC.
Invest New Drugs. 2010;28(1):102-5.
We report a case of grade 2 proteinuria, occurred fifteen days after the first administration of an anti-integrin monoclonal antibody associated to standard doses of carboplatin/paclitaxel and to a single dose of zoledronic acid in a patient treated in first line setting for a metastatic non small cell lung cancer.