Polycythemia vera

Polycythemia vera (PV) is an acquired myeloproliferative disorder characterized by an elevated absolute red blood cell mass caused by uncontrolled red blood cell production, frequently associated with uncontrolled white blood cell and platelet production.

Stroke

Sudden impairment of blood flow to a part of the brain due to occlusion or rupture of an artery to the brain.


Total: 3

                       


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PMID (PMCID)
25401994
 MALE Middle Aged
Jak2 mutation-positive polycythemia vera presenting as central retinal artery occlusion.
Dhrami-Gavazi E, Lee W, Horowitz JD, Odel J, Mukkamala SK, Blumberg DM, Weiss M, Winn BJ.
Retin Cases Brief Rep. 2015;9(2):127-30.
Despite an initially normal hematocrit, the etiology of the central retinal artery occlusion and that of the nearly concomitant stroke in the right medial cerebral artery territory was confirmed by bone marrow biopsy to be polycythemia vera (positive JAK2 mutation).
23683307
(3668271)
 OTHER
Acute embolic cerebral ischemia as an initial presentation of polycythemia vera: a case report.
Zoraster RM, Rison RA.
J Med Case Rep. 2013;7:131.
While hemodilution has been generally discredited for general stroke management, it is potentially beneficial for patients with polycythemia vera and euvolemic hemodilution should be considered for the polycythemic patient with acute cerebral ischemia.
10809920
 FEMALE
Cerebral embolism in a patient with polycythemia rubra vera.
Segura T, Serena J, Teruel J, Davalos A.
Eur J Neurol. 2000;7(1):87-90.
Polycythemia rubra vera (PRV) is a rare haematological disorder that has a high risk of stroke, although the pathophysiological origin of the cerebral ischaemia in this disease is not well known.