Polycythemia vera

Polycythemia vera (PV) is an acquired myeloproliferative disorder characterized by an elevated absolute red blood cell mass caused by uncontrolled red blood cell production, frequently associated with uncontrolled white blood cell and platelet production.

Hepatosplenomegaly

Simultaneous enlargement of the liver and spleen.


Total: 1

                      


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PMID (PMCID)
20661915
MIXED_SAMPLE Adult
Effective management of accelerated phase myelofibrosis with low-dose splenic radiotherapy.
Pardanani A, Brown P, Neben-Wittich M, Tobin R, Tefferi A.
Am J Hematol. 2010;85(9):715-6.
The main cause of hepatosplenomegaly in primary (PMF), post polycythemia vera (post-PV MF), and post essential thrombocythemia (post-ET MF) myelofibrosis (MF) is extramedullary hematopoiesis (EMH).