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Polycythemia vera

Polycythemia vera (PV) is an acquired myeloproliferative disorder characterized by an elevated absolute red blood cell mass caused by uncontrolled red blood cell production, frequently associated with uncontrolled white blood cell and platelet production.

Melanonychia

Brown or black discoloration of the nails.

Total: 1

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PMID (PMCID)
21987143	MALE
	Cutaneous effects after prolongaded use of hydroxyurea in Polycythemia Vera.
	Franca ER, Teixeira MA, Matias Kde F, Antunes DE, Braz Rde A, Silva CE. An Bras Dermatol. 2011;86(4):751-4.
	We described a white, 75-year old man with diagnosis of Polycythemia Vera that in 11 years of treatment developed many cutaneous lesions: skin hyperpigmentation, atrophic lesions on forearms, longitudinal melanonychia of 20 nails, right forearm ulcer, cutaneous xerosis, ichthyosis and auricular spinocellular carcinoma.