Polycythemia vera

Polycythemia vera (PV) is an acquired myeloproliferative disorder characterized by an elevated absolute red blood cell mass caused by uncontrolled red blood cell production, frequently associated with uncontrolled white blood cell and platelet production.

Gangrene

A serious and potentially life-threatening condition that arises when a considerable mass of body tissue dies (necrosis).


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PMID (PMCID)
19902720
 FEMALE
Peripheral arterial thrombosis with presence of anti-centromere antibodies and polycythemia vera.
Pillai U, Muzaffar J, Uppaluri C.
Mo Med. 2009;106(5):369-72.
We report a patient with digital gangrene, who was asymptomatic before this episode and was found to have both ACA positivity and Polycythemia Vera.
696149
 MALE Adult
Polycythemia vera as a cause of ischemic digital necrosis.
Fagrell B, Mellstedt H.
Acta Chir Scand. 1978;144(3):129-32.
Two patients with polycythemia vera and peripheral gangrene as the only clinical sign of the disease are described.