Proteus syndrome

Proteus syndrome (PS) is a very rare and complex hamartomatous overgrowth disorder characterized by progressive overgrowth of the skeleton, skin, adipose, and central nervous systems.

Scoliosis

The presence of an abnormal lateral curvature of the spine.


Total: 15

                       


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PMID (PMCID)
23559393
 FEMALE Child
Proteus syndrome revealing itself after the treatment of a bilateral subdural haematoma.
El Hassani Y, Jenny B, Pittet-Cuenod B, Bottani A, Scolozzi P, Ozsahin Ayse H, Rilliet B.
Childs Nerv Syst. 2013;29(10):1927-31.
Other manifestations of Proteus syndrome, such as a right hypertrophy of the face with hypoplasia of its middle third, a pigmented epidermal nevus and asymmetric limbs and scoliosis, appeared progressively over time.
22223075
 MALE Child
A case of Proteus syndrome with severe spinal canal stenosis, scoliosis, and thoracic deformity associated with tethered cord.
Yamamoto A, Kikuchi Y, Yuzurihara M, Kubota M, O'uchi T.
Jpn J Radiol. 2012;30(4):336-9.
A case of Proteus syndrome with severe spinal canal stenosis, scoliosis, and thoracic deformity associated with tethered cord.
22223075
 MALE Child
A case of Proteus syndrome with severe spinal canal stenosis, scoliosis, and thoracic deformity associated with tethered cord.
Yamamoto A, Kikuchi Y, Yuzurihara M, Kubota M, O'uchi T.
Jpn J Radiol. 2012;30(4):336-9.
Vertebral overgrowth with severe spinal canal stenosis is unusual, although scoliosis with abnormal vertebral bodies is one of the typical features of Proteus syndrome.
22223075
 MALE Child
A case of Proteus syndrome with severe spinal canal stenosis, scoliosis, and thoracic deformity associated with tethered cord.
Yamamoto A, Kikuchi Y, Yuzurihara M, Kubota M, O'uchi T.
Jpn J Radiol. 2012;30(4):336-9.
We report a case of Proteus syndrome with severe spinal canal stenosis, scoliosis, cervical kyphosis, and thoracic deformity with airway obstruction because of asymmetrical overgrowth of vertebrae and ribs associated with a tethered cord, lipomas, strawberry hemangioma, flat nasal bridge, and bilateral hypoplasty of the first metatarsal bones with hyperplasty of soft tissue.
16238085
 MALE
Paraparesis caused by an angiolipomatous hamartoma in an adolescent with Proteus syndrome and scoliosis.
White NJ, Cochrane DD, Beauchamp R.
J Neurosurg. 2005;103(3 Suppl):282-4.
A review of the literature suggests that regular follow up, including serial MR imaging, is indicated in children with Proteus syndrome and scoliosis.
16238085
 MALE
Paraparesis caused by an angiolipomatous hamartoma in an adolescent with Proteus syndrome and scoliosis.
White NJ, Cochrane DD, Beauchamp R.
J Neurosurg. 2005;103(3 Suppl):282-4.
Paraparesis caused by an angiolipomatous hamartoma in an adolescent with Proteus syndrome and scoliosis.
16035717
 FEMALE Child
Recalcitrant scoliosis in Proteus syndrome.
Yazar T, Cebesoy O, Basarir K, Karadeniz E.
Acta Orthop Belg. 2005;71(3):372-4.
Proteus syndrome is a rare congenital condition with various clinical features such as hemihypertrophy, macrodactyly, subcutaneous masses, brain-like hyperplasia of the soles and/or palms, epidermal naevi and scoliosis with other mesodermal malformations.
11586023
 FEMALE
Proteus syndrome.
Yasuda H, Yamamoto O, Hirokawa H, Asahi M, Kashimura M, Sakai A.
Dermatology. 2001;203(2):180-4.
A case of Proteus syndrome is presented, in which severe hemihypertrophy of the left trunk and left lower extremity, scoliosis, endometriosis and huge bizarre-shaped body tumors were observed.
11568716
 MALE Infant
Scoliosis in Proteus syndrome: case report.
Takebayashi T, Yamashita T, Yokogushi K, Yokozawa H, Cavanaugh JM.
Spine (Phila Pa 1976). 2001;26(17):E395-8.
Proteus syndrome, a rare hamartomatous disorder first coined by Wiedemann, manifests many clinical morphologic abnormalities including scoliosis.
11568716
 MALE Infant
Scoliosis in Proteus syndrome: case report.
Takebayashi T, Yamashita T, Yokogushi K, Yokozawa H, Cavanaugh JM.
Spine (Phila Pa 1976). 2001;26(17):E395-8.
Scoliosis in Proteus syndrome: case report.
11568716
 MALE Infant
Scoliosis in Proteus syndrome: case report.
Takebayashi T, Yamashita T, Yokogushi K, Yokozawa H, Cavanaugh JM.
Spine (Phila Pa 1976). 2001;26(17):E395-8.
To present the characteristics of scoliosis associated with Proteus syndrome, and to investigate the mechanisms that cause it.
11568716
 MALE Infant
Scoliosis in Proteus syndrome: case report.
Takebayashi T, Yamashita T, Yokogushi K, Yokozawa H, Cavanaugh JM.
Spine (Phila Pa 1976). 2001;26(17):E395-8.
Scoliosis with Proteus syndrome seems to be based on hemihypertrophy, with no influence of mechanical stress.
9084553
 MALE
Acquired tracheomalacia--a case report.
Kang FC, Tsai YC, Jiang CY, Chen HP, Chang CL.
Acta Anaesthesiol Sin. 1996;34(4):239-42.
We present a case of acquired tracheomalacia in a 15-year-old boy, a victim of Proteus syndrome (hemihypertrophy, subcutaneous tumors, and macrodactyly), who had congenital scoliosis with secondary chronic restrictive pulmonary disease, for which he was admitted to our hospital for surgical correction of the spine.
7754774
 FEMALE Child
Proteus syndrome with renal involvement.
Sato T, Ota M, Miyazaki S.
Acta Paediatr Jpn. 1995;37(1):81-3.
The patient had hemihypertrophy, scoliosis, overgrowth of lower extremities, partial macrodactyly, subcutaneous lipoma, and pigmented nevi compatible with the Proteus syndrome.
8345255
 MALE
Macrodactyly in Proteus syndrome.
Miura H, Uchida Y, Ihara K, Sugioka Y.
J Hand Surg Br. 1993;18(3):308-9.
A case of Proteus syndrome in a 13-year-old boy with macrodactyly, hemihypertrophy, exostosis of the skull, epidermal naevi, palmar and plantar masses, and scoliosis is reported.