Rett syndrome

Rett syndrome (RTT) is a severe neurodevelopmental disorder affecting the central nervous system.

Anxiety

Intense feelings of nervousness, tenseness, or panic, often in reaction to interpersonal stresses; worry about the negative effects of past unpleasant experiences and future negative possibilities; feeling fearful, apprehensive, or threatened by uncertainty; fears of falling apart or losing control.


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(per page)
PMID (PMCID)
27899087
(5129599)
FEMALE
Paradoxical physiological responses to propranolol in a Rett syndrome patient: a case report.
Santosh PJ, Bell L, Lievesley K, Singh J, Fiori F.
BMC Pediatr. 2016;16(1):194.
Rett Syndrome (RTT), caused by a loss-of-function in the epigenetic modulator: X-linked methyl-CpG binding protein 2 (MeCP2), is a pervasive neurological disorder characterized by compromised brain functions, anxiety, severe mental retardation, language and learning disabilities, repetitive stereotyped hand movements and developmental regression.