Rett syndrome

Rett syndrome (RTT) is a severe neurodevelopmental disorder affecting the central nervous system.

Osteopenia

Osteopenia is a term to define bone density that is not normal but also not as low as osteoporosis. By definition from the World Health Organization osteopenia is defined by bone densitometry as a T score -1 to -2.5.


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PMID (PMCID)
23828127
 FEMALE Infant
Osteoporosis in Rett syndrome: a case study presenting a novel management intervention for severe osteoporosis.
Lotan M, Reves-Siesel R, Eliav-Shalev RS, Merrick J.
Osteoporos Int. 2013;24(12):3059-63.
Individuals with Rett syndrome (RS) have been shown to have low bone mineral density (or osteopenia) at a young age.