Rett syndrome

Rett syndrome (RTT) is a severe neurodevelopmental disorder affecting the central nervous system.

Spasticity

A motor disorder characterized by a velocity-dependent increase in tonic stretch reflexes with increased muscle tone, exaggerated (hyperexcitable) tendon reflexes.


Total: 4

                       


(per page)
PMID (PMCID)
12819544
 FEMALE Adult
Intrathecal baclofen for spasticity management in Rett syndrome.
Kadyan V, Clairmont AC, George RJ, Johnson EW.
Am J Phys Med Rehabil. 2003;82(7):560-2.
Intrathecal baclofen for spasticity management in Rett syndrome.
12819544
 FEMALE Adult
Intrathecal baclofen for spasticity management in Rett syndrome.
Kadyan V, Clairmont AC, George RJ, Johnson EW.
Am J Phys Med Rehabil. 2003;82(7):560-2.
Intrathecal baclofen is an effective option in managing severe spasticity from Rett syndrome.
12819544
 FEMALE Adult
Intrathecal baclofen for spasticity management in Rett syndrome.
Kadyan V, Clairmont AC, George RJ, Johnson EW.
Am J Phys Med Rehabil. 2003;82(7):560-2.
Presented is a case report of a 32-yr-old white woman with Rett syndrome, diagnosed before the age of 2 yr, and significant spasticity that was successfully managed with intrathecal baclofen.
12615169
 MIXED_SAMPLE Adult
Neurodevelopmental disorders in males related to the gene causing Rett syndrome in females (MECP2).
Moog U, Smeets EE, van Roozendaal KE, Schoenmakers S, Herbergs J, Schoonbrood-Lenssen AM, Schrander-Stumpel CT.
Eur J Paediatr Neurol. 2003;7(1):5-12.
A history of early hypotonia evolving into severe spasticity, slowing of head growth, breathing irregularities and good visual interactive behaviour were highly suggestive of Rett syndrome.