Q fever

Q fever, caused by <i>Coxiella burnetii</i>, is a bacterial zoonosis with a wide clinical spectrum that can be life-threatening and, in some cases, can become chronic.

Pneumonia

Inflammation of any part of the lung parenchyma.


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PMID (PMCID)
28819912
 FEMALE Adult
A case of Q fever with erythema nodosum.
Meriglier E, Asquier L, Roblot F, Roblot P, Landron C.
Infection. 2018;46(1):127-129.
Acute Q fever is asymptomatic in 60% of the patients, while the reminder may present with fever, pneumoniae, and hepatitis.
29619325
(5881519)
 OTHER
Doxycycline desensitization in chronic Q fever-A critical tool for the clinician.
Caplunik-Pratsch AL, Potasman I, Kessel A, Paz A.
IDCases. 2018;11:70-72.
We present the case of a 458201year old woman with acute Q fever pneumonia who progressed to the chronic phase of the disease despite azithromycin therapy.
28739619
 FEMALE Middle Aged
Q fever prosthetic joint infection.
Weisenberg S, Perlada D, Peatman T.
BMJ Case Rep. 2017;2017:.
Most patients with Q fever experience a non-specific febrile illness, hepatitis or pneumonia.
27666914
 MALE Adult
Acute Q Fever Pneumonia.
Panjwani A, Shivaprakasha S, Karnad D.
J Assoc Physicians India. 2015;63(12):83-84.
We report a case of acute Q fever related pneumonia and this appears to be the first reported case of pneumonia due to C. burnetii infection in India.
27666914
 MALE Adult
Acute Q Fever Pneumonia.
Panjwani A, Shivaprakasha S, Karnad D.
J Assoc Physicians India. 2015;63(12):83-84.
We report a case of acute Q fever related pneumonia and this appears to be the first reported case of pneumonia due to C. burnetii infection in India.
25770747
 MIXED_SAMPLE Adult
Familial Q fever clustering with variable manifestations imitating infectious and autoimmune disease.
Abu Rmeileh A, Khoury T, Meir K, Drori A, Shalit M, Benenson S, Elinav H.
Clin Microbiol Infect. 2015;21(5):459-63.
Q fever, caused by Coxiella burnetii, can present as an outbreak of acute disease ranging from asymptomatic disease, pneumonia, hepatitis or fever of unknown origin, which can progress to a chronic disease, most frequently endocarditis.
26099187
 MALE Middle Aged
[Prolonged disease in a farmer with simultaneous Q fever pneumonia and subacute hypersensitivity pneumonitis].
Nielsen ME, Hilberg O, Bendstrup E.
Ugeskr Laeger. 2015;177(26):.
[Prolonged disease in a farmer with simultaneous Q fever pneumonia and subacute hypersensitivity pneumonitis].
24767204
 MALE Adult
[Q fever endocarditis: a report of four cases and literature review].
Zhou B, Wang H, Fan H, Liu X, Li T.
Zhonghua Nei Ke Za Zhi. 2014;53(3):184-7.
Endocarditis is the most common form of chronic Q fever, which is easily misdiagnosed because its blood culture is negative and may accompanied with varied manifestation such as pneumonia and liver injury.
22850965
 MALE Adult
Coxiella burnetii, the agent of Q fever in Brazil: its hidden role in seronegative arthritis and the importance of molecular diagnosis based on the repetitive element IS1111 associated with the transposase gene.
Rozental T, Mascarenhas LF, Rozenbaum R, Gomes R, Mattos GS, Magno CC, Almeida DN, Rossi MI, Favacho AR, de Lemos ER.
Mem Inst Oswaldo Cruz. 2012;107(5):695-7.
This study reports the sequencing of the repetitive element IS1111 of the transposase gene of C. burnetii from blood and bronchoalveolar lavage (BAL) samples from a patient with severe pneumonia following methotrexate therapy, resulting in the molecular diagnosis of Q fever in a patient who had been diagnosed with active seronegative polyarthritis two years earlier.
22116335
 MALE
Acute Q fever presenting as antiphospholipid syndrome, pneumonia, and acalculous cholecystitis and masquerading as Mycoplasma pneumoniae and hepatitis C viral infections.
Lee CH, Chuah SK, Pei SN, Liu JW.
Jpn J Infect Dis. 2011;64(6):525-7.
Acute Q fever presenting as antiphospholipid syndrome, pneumonia, and acalculous cholecystitis and masquerading as Mycoplasma pneumoniae and hepatitis C viral infections.
22116335
 MALE
Acute Q fever presenting as antiphospholipid syndrome, pneumonia, and acalculous cholecystitis and masquerading as Mycoplasma pneumoniae and hepatitis C viral infections.
Lee CH, Chuah SK, Pei SN, Liu JW.
Jpn J Infect Dis. 2011;64(6):525-7.
Acute Q fever presenting as antiphospholipid syndrome, pneumonia, and acalculous cholecystitis and masquerading as Mycoplasma pneumoniae and hepatitis C viral infections.
22116335
 MALE
Acute Q fever presenting as antiphospholipid syndrome, pneumonia, and acalculous cholecystitis and masquerading as Mycoplasma pneumoniae and hepatitis C viral infections.
Lee CH, Chuah SK, Pei SN, Liu JW.
Jpn J Infect Dis. 2011;64(6):525-7.
We report a case of Q fever-related antiphospholipid syndrome in a patient presenting with acalculous cholecystitis and pneumonia.
21329539
 MIXED_SAMPLE Infant, Newborn
[Chronic Q fever during pregnancy].
Munster JM, Hamilton CJ, Leenders AC, Lestrade PJ.
Ned Tijdschr Geneeskd. 2011;155:A2781.
In retrospect the pneumonia appeared to be a manifestation of an acute Q fever infection.
21519168
 MALE Adult
[Q fever as a cause of acute hepatitis accompanying fever].
Lee HJ, Kim JH, Yoon EL, Lee YS, Yeon JE, Byun KS, Kim BH, Ryu Y.
Korean J Gastroenterol. 2011;57(3):189-93.
Common manifestations of acute Q fever usually present as influenza-like illness, pneumonia and occasionally hepatitis.
19755196
 FEMALE
Mycoplasma pneumoniae community-acquired pneumonia (CAP) in the elderly: Diagnostic significance of acute thrombocytosis.
Cunha BA, Pherez FM.
Heart Lung. 2009;38(5):444-9.
Acute thrombocytosis due to M. pneumoniae and Q fever occurs during weeks 1 and 2 of the infection.
19755196
 FEMALE
Mycoplasma pneumoniae community-acquired pneumonia (CAP) in the elderly: Diagnostic significance of acute thrombocytosis.
Cunha BA, Pherez FM.
Heart Lung. 2009;38(5):444-9.
In a patient with CAP, acute thrombocytosis is usually associated with Q fever pneumonia and less commonly with M. pneumoniae.
19755196
 FEMALE
Mycoplasma pneumoniae community-acquired pneumonia (CAP) in the elderly: Diagnostic significance of acute thrombocytosis.
Cunha BA, Pherez FM.
Heart Lung. 2009;38(5):444-9.
In a patient with CAP, acute thrombocytosis is usually associated with Q fever pneumonia and less commonly with M. pneumoniae.
19755196
 FEMALE
Mycoplasma pneumoniae community-acquired pneumonia (CAP) in the elderly: Diagnostic significance of acute thrombocytosis.
Cunha BA, Pherez FM.
Heart Lung. 2009;38(5):444-9.
If Q fever can be excluded on the basis of a recent/proximate zoonotic vector contact history, then acute thrombocytosis is an important clue to M. pneumoniae CAP.
19577708
 FEMALE Adult
Severe Q fever community-acquired pneumonia (CAP) mimicking Legionnaires' disease: Clinical significance of cold agglutinins, anti-smooth muscle antibodies and thrombocytosis.
Cunha BA, Nausheen S, Busch L.
Heart Lung. 2009;38(4):354-62.
The 2 atypical pneumonias that most closely resemble each other clinically are Q fever and Legionnaires' disease.
19577708
 FEMALE Adult
Severe Q fever community-acquired pneumonia (CAP) mimicking Legionnaires' disease: Clinical significance of cold agglutinins, anti-smooth muscle antibodies and thrombocytosis.
Cunha BA, Nausheen S, Busch L.
Heart Lung. 2009;38(4):354-62.
Severe Q fever community-acquired pneumonia (CAP) mimicking Legionnaires' disease: Clinical significance of cold agglutinins, anti-smooth muscle antibodies and thrombocytosis.