Retinoblastoma

A rare eye tumor disease representing the most common intraocular malignancy in children. It is a life threatening neoplasia but is potentially curable and it can be hereditary or non hereditary, unilateral or bilateral.

Gliosis

Gliosis is the focal proliferation of glial cells in the central nervous system.


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PMID (PMCID)
30320092
 OTHER
Atypical Retinal Pigment Epithelial Hyperplasia and Glial Proliferation Masquerading as Progressive Recurrent Retinoblastoma: A Case Report Review and Clinicopathologic Correlation.
Zolfaghari E, Kim JW, Krishnan S, Chevez-Barrios P, Berry JL.
Ocul Oncol Pathol. 2018;4(2):116-121.
Herein we report extensive RPE hyperplasia and gliosis during laser therapy for a focal scar recurrence, which presented as a progressive retinal opacification mimicking active retinoblastoma.
15341098
 MALE Adult
[Retinal tumors of the adult--two case reports].
Carstocea B, Gafencu O, Macovei L.
Oftalmologia. 2004;48(2):37-41.
Most frequently, retinal tumors that affect adults are rare, benign lesions that arise from vascular structures (hemangioma), neuroglial structures (astrocytoma, massive gliosis of the retina) or neuroepithelial cells (occasional forms of retinoblastoma that spontaneously stop growing and do not achieve or lose their malignant character).
677667
 MALE Adult
Presumed spontaneously regressed retinoblastoma.
Benson WE, Cameron JD, Furgiuele FP, Felberg NT, Yanoff M.
Ann Ophthalmol. 1978;10(7):897-9.
The diagnosis of regressed retinoblastoma should be considered where the pathologic diagnosis of an enucleated eye is massive gliosis of the retina, but where no known cause is present.