Retinoblastoma

A rare eye tumor disease representing the most common intraocular malignancy in children. It is a life threatening neoplasia but is potentially curable and it can be hereditary or non hereditary, unilateral or bilateral.

Rosette

A halo or spoke-wheel arrangement of cells surrounding a central core or hub. The central hub may consist of an empty-appearing lumen or a space filled with cytoplasmic processes. The cytoplasm of each of the cells in the rosette is often wedge-shaped with the apex directed toward the central core; the nuclei of the cells participating in the rosette are peripherally positioned and form a ring or halo around the hub.

Total: 8

(per page)

PMID (PMCID)
29758594	MALE	Infant
	PHOX2B is a reliable immunomarker in distinguishing peripheral neuroblastic tumours from CNS embryonal tumours.
	Alexandrescu S, Paulson V, Dubuc A, Ligon A, Lidov HG. Histopathology. 2018;73(3):483-491.
	PHOX2B immunostain was performed on 29 paediatric cases, with adequate controls: one retroperitoneal embryonal tumour in a child with retinoblastoma (index 1), one posterior fossa embryonal tumour in a child with a neuroblastoma (index 2), seven medulloblastomas, four atypical teratoid/rhabdoid tumours (ATRT), four retinoblastomas, six pineoblastomas, four embryonal tumours with multilayered rosettes (ETMR) and two CNS embryonal tumours, not elsewhere classified.
29758594	MALE	Infant
	PHOX2B is a reliable immunomarker in distinguishing peripheral neuroblastic tumours from CNS embryonal tumours.
	Alexandrescu S, Paulson V, Dubuc A, Ligon A, Lidov HG. Histopathology. 2018;73(3):483-491.
	PHOX2B immunostain was performed on 29 paediatric cases, with adequate controls: one retroperitoneal embryonal tumour in a child with retinoblastoma (index 1), one posterior fossa embryonal tumour in a child with a neuroblastoma (index 2), seven medulloblastomas, four atypical teratoid/rhabdoid tumours (ATRT), four retinoblastomas, six pineoblastomas, four embryonal tumours with multilayered rosettes (ETMR) and two CNS embryonal tumours, not elsewhere classified.
24881618 (4065523)	FEMALE	Infant
	A new rosette in retinoblastoma.
	Das D, Bhattacharjee K, Barthakur SS, Tahiliani PS, Deka P, Bhattacharjee H, Deka A, Paul R. Indian J Ophthalmol. 2014;62(5):638-41.
	In the present case report, a third new type of rosette was identified in a differentiated retinoblastoma which had an unusual anterior segment involvement.
24881618 (4065523)	FEMALE	Infant
	A new rosette in retinoblastoma.
	Das D, Bhattacharjee K, Barthakur SS, Tahiliani PS, Deka P, Bhattacharjee H, Deka A, Paul R. Indian J Ophthalmol. 2014;62(5):638-41.
	Since a hundred years, we have been observing two typical true rosettes in retinoblastoma in the form of Flexner-Wintersteiner (FW) and Homer Wright (HW) rosettes and in many occasions pseudorosettes have been documented.
24881618 (4065523)	FEMALE	Infant
	A new rosette in retinoblastoma.
	Das D, Bhattacharjee K, Barthakur SS, Tahiliani PS, Deka P, Bhattacharjee H, Deka A, Paul R. Indian J Ophthalmol. 2014;62(5):638-41.
	Since a hundred years, we have been observing two typical true rosettes in retinoblastoma in the form of Flexner-Wintersteiner (FW) and Homer Wright (HW) rosettes and in many occasions pseudorosettes have been documented.
15480771	MALE	Infant
	Second primary osteosarcoma with rosette-like structure in a patient with retinoblastoma.
	Okada K, Hasegawa T, Tateishi U, Itoi E. Virchows Arch. 2004;445(4):421-4.
	Second primary osteosarcoma with rosette-like structure in a patient with retinoblastoma.
3891392	FEMALE	Infant
	Glial cell component in retinoblastoma.
	Craft JL, Sang DN, Dryja TP, Brockhurst RJ, Robinson NL, Albert DM. Exp Eye Res. 1985;40(5):647-59.
	This tumor is presented because of its unusual rosette structures and because it confirms recent reports describing a glial cell component in retinoblastoma.
6674872	MALE	Infant
	Histopathological and tissue culture studies of a melanizing cell line derived from a retinoblastoma.
	Smith PJ, Ablett GA, Sheridan JW. Pathology. 1983;15(4):431-5.
	Histological examination of the enucleated eye of a 7-mth-old child revealed a retinoblastoma with areas of rosette formation as well as focal areas of melanin pigmentation.