Mixed connective tissue disease

Mixed connective tissue disease (MCTD) is a rare connective tissue disorder combining clinical features of systemic lupus erythematosus (SLE), systemic sclerosis (SSc), polymyositis (PM) (see these terms) and/or rheumatoid arthritis (RA).

Arthritis

Inflammation of a joint.


Total: 8

                       


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PMID (PMCID)
27162291
 MIXED_SAMPLE Adult
[Autoimmune diseases with the presence of anti-ku antibodies - analysis of three cases].
Wielosz E, Majdan M, Jeleniewicz R, Mazurek M.
Wiad Lek. 2016;69(1):24-6.
Case 1, a 77-year-old man, with the diagnosis of mixed connective tissue disease according to Raynaud`s phenomenon, myositis, arthritis and presence of a-ribonucleoprotein antibodies.
18789123
 MALE Child
A case report of successful treatment with immunoadsorption onto protein A in mixed connective tissue disease in childhood.
Rummler S, Althaus K, Maak B, Barz D.
Ther Apher Dial. 2008;12(4):337-42.
An 11-year-old male patient suffering mixed connective tissue disease with life-threatening pulmonary arterial hypertension, progressive heart failure (New York Heart Association class III-IV), skin ulcers, Raynaud's phenomenon and arthritis, showing no improvement after intensive immunosuppressive therapy or high dose steroids, was treated with immunoadsorption onto protein A.
12872451
(4531616)
 FEMALE Adult
Mycobacterium avium arthritis with extra-articular abscess in a patient with mixed connective tissue disease.
Lee CW, Sung HD, Choi BM, Kim CW, Jun SJ, Min SJ.
Korean J Intern Med. 2003;18(2):119-21.
A case of Mycobacterium avium arthritis in a 39-year-old female patient with mixed connective tissue disease (MCTD) was reported.
11455666
 FEMALE Middle Aged
[Cerebral tuberculosis in a patient with Sharp's syndrome].
Gaul C, Schmid A, Mohr W, Lohoff M, Heckmann JG, Erbguth F, Neundorfer B.
Dtsch Med Wochenschr. 2001;126(25-26):750-3.
She had a 9-year history of mixed connective tissue disease (MCTD, Sharp's syndrome) predominantly presenting with pulmonary symptoms and destructive arthritis.
9396373
 FEMALE Adult
[Two cases with SLE and MCTD developed after a long period of chronic arthritis that was initially diagnosed as JRA].
Takei S, Maeno N, Shigemori M, Nakae Y, Mori H, Nerome Y, Imanaka H, Hokonohara M, Miyata K.
Ryumachi. 1997;37(5):702-8.
In order to discuss the diversity of clinical features and the difficulty in diagnosis of children with juvenile rheumatoid arthritis (JRA), we present two cases who have documented the development of systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD) after a long period of disease characterized only by arthritis that was initially diagnosed as JRA.
3207385
 FEMALE Adult
Intra-articular apatite deposition in mixed connective tissue disease: crystallographic and technetium scanning characteristics.
Hutton CW, Maddison PJ, Collins AJ, Berriman JA.
Ann Rheum Dis. 1988;47(12):1027-30.
An acute arthritis in a patient with mixed connective tissue disease (MCTD) was found to be associated with intra-articular deposition of carbonated hydroxyapatite crystals.
3705774
 MIXED_SAMPLE Adult
[Rheumatoid arthritis, progressive systemic sclerosis without skin involvement and mixed collagen disease in a family. Clinical description of a mother and her 3 adult children--studies of HLA antigens and review of the literature].
Stockmann G, Franke M, Kasulke D.
Z Rheumatol. 1986;45(1):16-25.
After 2 years rheumatoid arthritis developed in the mother of the family (Patient 3) and another 2 years later the second son (Patient 4) was affected by mixed connective tissue disease (MCTD) with arthritis, Raynaud's phenomenon, aperistalsis of the esophagus and a high titer of antibody to extractable nuclear antigen (ENA).
1086651
 MIXED_SAMPLE Middle Aged
Mixed connective tissue disease.
Minkin W, Rabhan N.
Arch Dermatol. 1976;112(11):1535-8.
Three patients with mixed connective tissue disease (MCTD) had clinical features that included a high incidence of Raynaud phenomenon, arthritis, myositis, and swollen hands.