Mixed connective tissue disease

Mixed connective tissue disease (MCTD) is a rare connective tissue disorder combining clinical features of systemic lupus erythematosus (SLE), systemic sclerosis (SSc), polymyositis (PM) (see these terms) and/or rheumatoid arthritis (RA).

Pericarditis

Inflammation of the sac-like covering around the heart (pericardium).


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PMID (PMCID)
23257531
 FEMALE Middle Aged
Rapidly progressive respiratory failure in mixed connective tissue disease: report of an autopsy case.
Watanabe Y, Koyama S, Moriguchi M, Miwa C, Shiraishi M, Nomura M, Nokubi M, Terai C, Kawabata Y.
Intern Med. 2012;51(24):3415-9.
The case was diagnosed as mixed connective tissue disease (MCTD) due to presence of swollen fingers, Raynaud's phenomenon, muscle weakness, positive anti-U1RNP antibody, pericarditis and interstitial pneumonia.
15559324
 FEMALE Middle Aged
[A case of mixed connective tissue disease successfully treated for hemophagocytic syndrome with intermittent intravenous injection of cyclophosphamide].
Kato M, Sato S, Suzuki M, Oka H, Kaneko Y, Yasuoka H, Nojima T, Suwa A, Hirakata M, Ikeda Y.
Nihon Rinsho Meneki Gakkai Kaishi. 2004;27(5):345-9.
Then she was transferred to Keio University Hospital and she was diagnosed as having mixed connective tissue disease (MCTD) manifestating myositis, interstitial pneumonia, pulmonary hypertension and pericarditis.
1623882
 FEMALE
Pleuritis-pericarditis--an unusual initial manifestation of mixed connective tissue disease.
Beier JM, Nielsen HL, Nielsen D.
Eur Heart J. 1992;13(6):859-61.
Pleuritis-pericarditis--an unusual initial manifestation of mixed connective tissue disease.
2290169
 FEMALE Middle Aged
Purulent pericarditis and cardiac tamponade caused by Nocardia asteroides in mixed connective tissue disease.
Leung WH, Wong KL, Lau CP, Wong CK.
J Rheumatol. 1990;17(9):1237-9.
We describe the first reported case of purulent pericarditis with cardiac tamponade as the initial presentation of systemic nocardiosis in a patient with mixed connective tissue disease.
3814202
 FEMALE Adult
Nuclear ribonucleoprotein immune complexes in pericardial fluid of a patient with mixed connective tissue disease.
Negoro N, Kanayama Y, Yasuda M, Okamura M, Amatsu K, Koda S, Takeda T, Inoue T.
Arthritis Rheum. 1987;30(1):97-101.
We performed immunopathologic studies of the pericarditis present in a patient with mixed connective tissue disease.