Sotos syndrome

Sotos syndrome is a rare multisystemic genetic disorder characterized by a typical facial appearance, overgrowth of the body in early life with macrocephaly, and mild to severe intellectual disability.

Hypertelorism

Interpupillary distance more than 2 SD above the mean (alternatively, the appearance of an increased interpupillary distance or widely spaced eyes).


合計: 1

                       


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PMID (PMCID)
22790336
 MALE
A case of Sotos syndrome treated with distraction osteogenesis in maxilla and mandible.
Takano M, Kasahara K, Ogawa C, Katada H, Sueishi K.
Bull Tokyo Dent Coll. 2012;53(2):75-82.
Sotos syndrome is inherited in an autosomal-dominant manner and is characterized by increased birth weight, excessive growth, advanced bone age, and distinctive facial features, including dolichocephaly, hypertelorism, and a prominent mandible.