Sotos syndrome

Sotos syndrome is a rare multisystemic genetic disorder characterized by a typical facial appearance, overgrowth of the body in early life with macrocephaly, and mild to severe intellectual disability.

Pes planus

A foot where the longitudinal arch of the foot is in contact with the ground or floor when the individual is standing; or, in a patient lying supine, a foot where the arch is in contact with the surface of a flat board pressed against the sole of the foot by the examiner with a pressure similar to that expected from weight bearing; or, the height of the arch is reduced.

Total: 2

(per page)

PMID (PMCID)
15087812	MALE
	Cervical instability in Sotos syndrome: a case report.
	Carlo W, Dormans JP. Spine (Phila Pa 1976). 2004;29(7):E153-6.
	Sotos syndrome, a rare overgrowth syndrome with slightly more than 300 cases reported in the English literature to date, is characterized by a unique constellation of symptoms and signs including musculoskeletal findings such as scoliosis, pes planus, generalized ligamentous laxity, and increased growth rates.
9950366	MIXED_SAMPLE	Child
	Sotos syndrome and cutis laxa.
	Robertson SP, Bankier A. J Med Genet. 1999;36(1):51-6.
	Characteristics suggestive of connective tissue dysfunction have been described in Sotos syndrome and include joint hyperextensibility, pes planus, and a high arched palate.