Sotos syndrome

Sotos syndrome is a rare multisystemic genetic disorder characterized by a typical facial appearance, overgrowth of the body in early life with macrocephaly, and mild to severe intellectual disability.

Clumsiness

Lack of physical coordination resulting in an abnormal tendency to drop items or bump into objects.


合計: 2

                       


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PMID (PMCID)
7562459
 FEMALE Child
Cerebral gigantism (Sotos' syndrome). A rare cause of delayed walking and awkward gait.
Sobel E.
J Am Podiatr Med Assoc. 1995;85(9):497-9.
Throughout her life, this child has demonstrated all of the common features of Sotos' syndrome including large size at birth, excessive growth during childhood, dysmorphic craniofacial features, delay in motor and speech development, generalized clumsiness, and awkward gait.
2401112
 FEMALE Adult
[A case of cerebral gigantism with cerebellar atrophy].
Kitazawa K, Ikeda M, Tsukagoshi H.
Rinsho Shinkeigaku. 1990;30(5):520-3.
Though cerebral gigantism is often associated with clumsiness and incoordination, the etiology of the ataxia is poorly understood.