Hereditary spherocytosis

Hereditary spherocytosis is a congenital hemolytic anemia with a wide clinical spectrum (from symptom-free carriers to severe hemolysis) characterized by anemia, variable jaundice, splenomegaly and cholelithiasis.

Meningitis

Inflammation of the meninges.


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(per page)
PMID (PMCID)
10602897
 MIXED_SAMPLE Adult
Frequency of very late fatal sepsis after splenectomy for hereditary spherocytosis: impact of insufficient antibody response to pneumococcal infection.
Eber SW, Langendorfer CM, Ditzig M, Reinhardt D, Stohr G, Soldan W, Schroter W, Tchernia G.
Ann Hematol. 1999;78(11):524-8.
Within the past 7 years we have learned of four cases of sepsis or meningitis (three fatal) in adult patients with hereditary spherocytosis who had been splenectomized years earlier.