Hereditary spherocytosis

Hereditary spherocytosis is a congenital hemolytic anemia with a wide clinical spectrum (from symptom-free carriers to severe hemolysis) characterized by anemia, variable jaundice, splenomegaly and cholelithiasis.

Slurred speech

Abnormal coordination of muscles involved in speech.


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PMID (PMCID)
11483402
 MALE
Moyamoya syndrome with spherocytosis: effect of splenectomy on strokes.
Tokunaga Y, Ohga S, Suita S, Matsushima T, Hara T.
Pediatr Neurol. 2001;25(1):75-7.
A 3-year-old male patient with hereditary spherocytosis who developed moyamoya syndrome, presenting hemiplegia, and slurred speech is reported.