Hereditary spherocytosis

Hereditary spherocytosis is a congenital hemolytic anemia with a wide clinical spectrum (from symptom-free carriers to severe hemolysis) characterized by anemia, variable jaundice, splenomegaly and cholelithiasis.

Hyperbilirubinemia

An increased amount of bilirubin in the blood.


Total: 8

                       


(per page)
PMID (PMCID)
29200157
 FEMALE Infant
An Infant With Unusually High Unconjugated Hyperbilirubinemia Due to Coexistence of Hereditary Spherocytosis and Gilbert Syndrome.
Butorac Ahel I, Baraba Dekanic K, Palcevski G, Roganovic J.
J Pediatr Hematol Oncol. 2018;40(2):e127-e128.
Here we present a 21-month-old girl with hereditary spherocytosis diagnosed at the age of 40 days with hyperbilirubinemia out of proportion of hemolysis which led to diagnosis of GS.
30207817
 FEMALE Infant, Newborn
Tokyo-1 Mutation: Hereditary Spherocytosis in a Hispanic Newborn Presenting as Early Onset Severe Hyperbilirubinemia.
Tan AW, Leung P, Patil UP.
Fetal Pediatr Pathol. 2018;37(4):296-300.
Tokyo-1 Mutation: Hereditary Spherocytosis in a Hispanic Newborn Presenting as Early Onset Severe Hyperbilirubinemia.
30207817
 FEMALE Infant, Newborn
Tokyo-1 Mutation: Hereditary Spherocytosis in a Hispanic Newborn Presenting as Early Onset Severe Hyperbilirubinemia.
Tan AW, Leung P, Patil UP.
Fetal Pediatr Pathol. 2018;37(4):296-300.
Hereditary spherocytosis in the Hispanic population does not often present with severe hyperbilirubinemia.
28321066
(5410476)
 MALE Young Adult
Gilbert Syndrome with Concomitant Hereditary Spherocytosis Presenting with Moderate Unconjugated Hyperbilirubinemia.
Aiso M, Yagi M, Tanaka A, Miura K, Miura R, Arizumi T, Takamori Y, Nakahara S, Maruo Y, Takikawa H.
Intern Med. 2017;56(6):661-664.
Both Gilbert syndrome and hereditary spherocytosis are hereditary diseases with a high frequency, and the hyperbilirubinemia may be exacerbated when these two diseases are concomitant.
21948575
 MALE Middle Aged
Severe jaundice due to coexistence of Dubin-Johnson syndrome and hereditary spherocytosis: a case report.
Korkmaz U, Duman AE, Ogutmen Koc D, Gurbuz Y, Dndar G, Ensaroglu F, Sener SY, Senturk O, Hulagu S.
Turk J Gastroenterol. 2011;22(4):422-5.
In this article, we report a patient who was evaluated for hyperbilirubinemia and liver function test abnormalities and diagnosed with Dubin-Johnson syndrome coexisting with hereditary spherocytosis.
20924216
(3304593)
 MALE Adult
A case of concomitant Gilbert's syndrome and hereditary spherocytosis.
Lee HJ, Moon HS, Lee ES, Kim SH, Sung JK, Lee BS, Jeong HY, Lee HY, Eu YJ.
Korean J Hepatol. 2010;16(3):321-4.
We describe moderate hyperbilirubinemia in a 28-year-old man who suffered from gallstones and splenomegaly, with combined disorders of hereditary spherocytosis (HS) and Gilbert's syndrome (GS).
3386065
 MIXED_SAMPLE Middle Aged
Preoperative computed tomography and scintigraphy to facilitate the detection of accessory spleen in patients with hematologic disorders.
Koyanagi N, Kanematsu T, Sugimachi K.
Jpn J Surg. 1988;18(1):101-4.
After the accessory spleen had been removed from the first patient, who had persistent hereditary spherocytosis and had undergone a splenectomy 15 months before, a postoperative decrease in hyperbilirubinemia was noted.
686044
 MALE
Extreme hyperbilirubinemia in a patient with hereditary spherocytosis, Gilbert's syndrome, and obstructive jaundice.
Katz ME, Weinstein IM.
Am J Med Sci. 1978;275(3):373-9.
Extreme hyperbilirubinemia in a patient with hereditary spherocytosis, Gilbert's syndrome, and obstructive jaundice.