Hereditary spherocytosis

Hereditary spherocytosis is a congenital hemolytic anemia with a wide clinical spectrum (from symptom-free carriers to severe hemolysis) characterized by anemia, variable jaundice, splenomegaly and cholelithiasis.

Microspherocytosis

The presence of erythrocytes that are sphere-shaped and reduced in size.


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PMID (PMCID)
8547071
 MIXED_SAMPLE
Band 4.2 Shiga: 317 CGC-->TGC in compound heterozygotes with 142 GCT-->ACT results in band 4.2 deficiency and microspherocytosis.
Kanzaki A, Yasunaga M, Okamoto N, Inoue T, Yawata A, Wada H, Andoh A, Hodohara K, Fujiyama Y, Bamba T, et al..
Br J Haematol. 1995;91(2):333-40.
Their red cell morphology exhibited microspherocytosis resembling classic hereditary spherocytosis (HS).
3250788
 MALE
What happens to the microspherocytosis of hereditary spherocytosis in folate deficiency?
Blecher TE.
Clin Lab Haematol. 1988;10(4):403-8.
What happens to the microspherocytosis of hereditary spherocytosis in folate deficiency?