Primary myelofibrosis

A rare myeloproliferative neoplasm characterized by stem-cell derived clonal over proliferation of mature myeloid lineages, such as erythrocytes, leukocytes, and megakaryocytes, with variable degrees of megakaryocyte atypia, associated with reticulin and/or collagen bone marrow fibrosis, osteosclerosis, ineffective erythropoiesis, angiogenesis, extramedullary hematopoiesis, and abnormal cytokine expression.

Hydronephrosis

Severe distention of the kidney with dilation of the renal pelvis and calices.

Total: 1

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PMID (PMCID)
11843900	FEMALE	Middle Aged
	Idiopathic myelofibrosis with extramedullary haemopoiesis involving the urinary bladder in a Chinese lady.
	Mak YK, Chan CH, So CC, Chan MK, Chu YC. Clin Lab Haematol. 2002;24(1):55-9.
	We report on a 54-year-old Chinese lady with a long history of idiopathic myelofibrosis who presented with gross haematuria and left hydronephrosis due to EMH in the bladder trigone.