Primary myelofibrosis

A rare myeloproliferative neoplasm characterized by stem-cell derived clonal over proliferation of mature myeloid lineages, such as erythrocytes, leukocytes, and megakaryocytes, with variable degrees of megakaryocyte atypia, associated with reticulin and/or collagen bone marrow fibrosis, osteosclerosis, ineffective erythropoiesis, angiogenesis, extramedullary hematopoiesis, and abnormal cytokine expression.

Asplenia

Absence (aplasia) of the spleen.


Total: 1

                       


(per page)
PMID (PMCID)
27403772
 FEMALE
A Rare Case of Primary Myelofibrosis in a 14-Year-Old Patient With Congenital Asplenia.
Khan M, Yin CC, Yates A, Newberry KJ, Verstovsek S.
J Pediatr Hematol Oncol. 2017;39(4):e196-e198.
A Rare Case of Primary Myelofibrosis in a 14-Year-Old Patient With Congenital Asplenia.