Primary myelofibrosis

A rare myeloproliferative neoplasm characterized by stem-cell derived clonal over proliferation of mature myeloid lineages, such as erythrocytes, leukocytes, and megakaryocytes, with variable degrees of megakaryocyte atypia, associated with reticulin and/or collagen bone marrow fibrosis, osteosclerosis, ineffective erythropoiesis, angiogenesis, extramedullary hematopoiesis, and abnormal cytokine expression.

Hemolytic anemia

A type of anemia caused by premature destruction of red blood cells (hemolysis).


Total: 2

                      


(per page)
PMID (PMCID)
3954534
MIXED_SAMPLE Middle Aged
Postsplenectomy pericardial effusion in two patients with myeloid metaplasia.
Nagler A, Brenner B, Argov S, Tatarsky I.
Arch Intern Med. 1986;146(3):600-1.
We describe two patients with agnogenic myeloid metaplasia and refractory hemolytic anemia in whom pericardial effusion appeared a few days after splenectomy.
524867
MIXED_SAMPLE Middle Aged
[Clinical characteristics of primary myelofibrosis].
Simeonov Ts, Petrov I.
Vutr Boles. 1979;18(6):108-12.
The clinical and hematologic variety, observed by the authors, provided grounds for the formation of the following variants of the primary myelofibrosis: myelemic-anemic form, form with leucosis transformation, form with sarcomatization, myelofibrosis with immune hemolytic anemia and myelofibrosis in aplastic state.